Hereditary ginfival fibromatosis: a 30 year follow up study in three genetations

Hereditary gingival fibromatosis [HGF] is a rare condition with undetermined etiology, thus is designated as idiopathic. Previous studies have revealed that the pattern of inheritance is autosomal dominant or [rarely] autosomal recessive. In our study a group of family members in three generations were followed for 30 years. This clinical and histological study was initiated by the extraction of remaining teeth and excision of the enlarged gingiva of the oldest member of the group. No recurrence happened after 30 years of follow-up. The other cases were operated twice during the primary and permanent dentition periods. After the second surgery, so far there has been no recurrence in any of the patients. In all cases the hyperplasia developed after the eruption of teeth and recurrence was observed after surgery in some of them who retained some teeth

[Evaluation of oral hygiene status in patients with Thalassemia in Dr. Sheikh hospital Mashhad in 2004]

Thalassemia disease is characterized by anemia with splenomegaly and bone change in the early ages of life. It is a blood disease with two subtypes; Alpha and Beta. The Disorder is in synthesis of RBC Globulins. According to genetic defects and globulin structure defect, this disease is classified into major,minor and intermediate. The aim of this study was evaluating the periodontal status and measuring the index of GI [Loe and Sillness] and OHI[DI-S and CI-S] compared with the control group. In this case-control study, 100 patients suffering from major thalassemia referring to Dr.Sheikh Pediatric Hospital as the case group and 100 patients referring to Mashhad dental school as the control group, were studied. The two groups matched in age, sex and tooth brushing frequency in a day. GI and OHI-S [CI-S and DI-S] were compared between the two groups. Statistical analysis was carried out by chi-square test. GI and DI were significantly different in the case group and GI and OHI-S were greater in 19-26 year old than other patients age groups. In patients undergone splenectomy, the periodontal diseases were more frequent than those without splenectomy. Discussion: These difference in GI and OHI between the case and control groups could be attributed to maxillo-facial disorders, mouth breathing, imperfect plaque control, as well as host immune factors due to splenectomy which predisposes these patients to periodontal diseases. Gingival diseases were more prevalent in patients with thalassemia due to more plaque formation

Prevalence of gingival and oral pigmentations in battery Industry workers in Khorasan province

Heavy metals absorbed systemically due to therapeutic use or occupational environments may discolor the gingiva and other areas of the oral mucosa. The purpose of this study was to determine the prevalence of oral and gingival pigmentations and blood lead level among battery industry workers and the relationship between them. In this cross-sectional study, fifty battery industry workers at Mashhad and Sabzevar were examined clinically regarding oral and gingival pigmentations. Then blood test was done for each of them and blood lead level was measured by graphite furnace atomic absorption technique at lmam Reza hospital laboratory. The data were analysed using chi-square test. In this study, there was not any significant difference between mean blood lead level of the workers of battery industry and that of the general population. Also, no significant changes in their oral pigmentation stata were detected clinically. It seems that due to new technologies in battery industry, saturnism among workers and other lead effects such as oral pigmentation [lead line] are not significant and their blood lead level is within the normal range