efficacy and side effect of some antiparasitic drugs in normal and S. mansoni infected mice

The present work aims to study the schistosomicidal and side effects of two antibilharzial drugs, the Praziquantel and Anthiomaline beside Fasinex which is used in this field for the first time and was effective in the treatment of fascioliasis. For this purpose, eight groups each of 30 mice were selected, then four groups were infected with S. mansoni cercariae. The treatment started at seven weeks postinfestation when the eggs were detected in the faeces for groups [I, II and III]. Praziquantel, [7.5 mg / mouse] and Fasinex [0.02 ml/mouse] were given per os as a single dose while Anthiomaline [6.5 mg / mouse] was given intramuscularly 3 injections / week for three weeks. The sacrifice of 8 mice for each group was carried out at one week post - treatment for worm load and biochemical analysis of SGOT and SGPT and after four weeks for histopathological examination of the liver and counting worms. The results showed that Praziquantel reduced the worm load by 97.65% and 99.73% at one and four weeks post treatment and had no destructive effect on normal liver function or hepatic-tissues. Also, it improved the liver function and the pathological picture of the liver, leaving only fibrosed egg granulomes, in the infected mice. Anthiomalin reduced the worm load by 81.86% and 96.27% after the same periods. It had slight destructive effect on the liver function in both normal and infected mice [elevation of SGOT and SGPT, also produced some swelling, vacuolation and hydropic changes in the hepatocytes of these groups]. Fasinex reduced the worm load by 52% and 60.33%. It had slight destructive effect in the liver function for normal and infected groups, but the drug had no toxic effect on the liver tissues in these groups

Contributions on the passalurus ambiguous life cycle and scanning electron microscopy studies

The life cycle of Passalurus ambiguus was studied experimentally. The 4th and 5th stage larvae were studied morphologically. The preparent period was determined and the seats of egg deposition were demonstrated. Histopathological studies were carried out from the infected region of the gastrointestinal tract and perianal region of experimentally infected rabbit. The anterior end of the obtained adult worms was studied by scanning electron microscope

Some contribution on the coccidial parasites in domesticated geese in dakahlia province-Egypt

Examination of 425 geese from different localities in Daqahlia Province during a period extended from May 1993 till April 1994 revealed that 25.88% were suffering from coccidiosis. Five species of Eimeria parasites were detected in the examined geese, one renal, E. truncata, and four intestinal, E. nocens, E. anseris, E. stigmosa and E. parvula [Tyzzeria parvula] with the ratio of 12.47%, 7.52%, 5.64% and 16.70%, respectively. The incidence rates of renal, intestinal and mixed coccidiosis in geese were 5.88%, 13.41% and 6.58%, respectively. E. truncata showed high rates of infection in winter season [24.65%], also all the intestinal Eimeria recorded were with high incidence in winter, except E. stigmosa which was high in autumn

Some fish trematodes from the Mediterranean Sea

Three digenetic trematodes were collected from marine fish. Opishthorchis gomtii and schikhobalotrema acutum were collected from the intestine of Mugil cephalus. Xenopera maculates was collected from the intestine of Mullus barbatus

Some studies on fasciola gigantica among naturally infected rabbits in Behera Governorate, Egypt

Fecal samples from 478 Baladi rabbits were examined for the presence of Fasciola gigantica eggs, to clarify its possible role in the epidemiology of this parasite. The seasonal dynamics of F. gigantica among naturally infected rabbits was stated, where the infestation role with this helminth parasite was found to be 16% in autumn, 29.6% in winter, 3.6% in spring and only 2.8% during the summer months. The detected eggs were viable and hatched after 7-9 days at 26C. The hatched miracidia were active and remained alive for 9 hours. Moreover, the pathological changes in the livers of naturally infested rabbits with F. gigantica were also discussed

Some studies on helminthes parasites of fresh water fish in Egypt

The present work deals with a study on helminth parasites which infest the three common Egyptian Nile fish [Clarias lazera, Bagrus bayad and Tilapia nilotica]. Out of the 471 collected fish from various water sources in Delta area 58.60% were found to harbor one or more types of parasites. The infestation rate was highest in Clarias lazera [85.54%] followed by Bagrus bayad [72.60%] and Tilapia nilotica [34.91%]. The effect of seasonal dynamics on the infestation rate with the different types of parasites was also studied. The morphological characters of some worms were illustrated

On heterakis supmaose [Schnider, 1866] recovered from the Egyptian house mouse [Mus musculus]

Heterakis spumosa, a nematode, was recovered from the caecum of two trapped house mice [Mus musculus], from the locality of Edfina, Behaira Governorate, Egypt. The parasite differed from other related species by its distince nephrological characters. Full description of that helminth parasite was given in the text. It is worth to mention that, the house mouse was considered as a new host for Heterakis spumosa worms

case record of spirometra erinacei in a stray dog in Zagazig

Spirometra erinacei was found in a stray dog. The general morphology, histology and biology were studied