Utility of beta-aroyl acrylic acid in heterocyclic synthesis

Beta-[4-bromobenzoyl] acrylic acid has been reacted with nitrogen nucleophiles namely ethanolamine and o-aminophenol and yielded the corresponding adduct l a,b. On the other hand, beta-[3,4dichlorobenzoyl] acrylic acid has been reacted with carbon nucleophiles namely o-dichlorobenzene under Friedel-Crafts conditions and yielded the corresponding adduct Ic. Behaviour of compounds 1 toward hydrazine hydrate, hydroxylamine and acetic anhydride has been investigated. Acylation and alkylation of pyridazinone derivative also have been described

Cardio-respiratory manifestation due to chronic occupational exposure to trichloroethylene

The hazardous effects of Trichloroethylene were studied on 125 exposed workers in the central Bank Note printing. The study shows that the level of air concentration of trichloroethylene is above the threshold limit value of this solvent. A significant obstructive ventilatory impairment and hypertension were found, in the exposed group. As regarding electrocardiographic [ECG] changes; there were high percentage of left ventricular hypertrophy, ischaemic heart diseases and arrhythmia in comparison to the control

industrial noise and accidents: a possible link

Industrial noise has been increminated by many investigators as an aetiologic factor of accidents. The possible link between accidents and noise in an automatic glass industry has been studied among 1500 workers. They were classifed according to exposure to noise at work into an exposed [1100 workers] and a control group [400 workers]. They were matched as regards age, sex, and work experience [duration of work]. They were also of the same socio-economic standard. Noise exposed workers had twice the incidence of accidents compared to the control group. Sites of injury predominant in accidents caused by noise were different from those caused by factors other than noise. The total days of absentiesm and the absence severity rate were significantly higher in accidents whether directly or indirectly caused by noise compared to those caused by other factors. Results are discussed and recommendations for a better work environment are suggested

Hearing loss among Egyptian workers exposed to noise in minthouse industry

This study was carried out in an industry where noise is a physical environmental pollutant. A sum of 148 male workers classified according to noise exposure into an exposed [98 workers] and a control group [50 workers]. On the day of examination, every worker had a questionnaire filled, an otologic examination and an audiogram. Noise level at different production sections was measured. The results of the study showed that noise-induced hearing loss was affected by age, duration of exposure and noise level at the investigated location. Statistically significant differences between the mean hearing loss for the exposed and the control workers were found. Recommendations to control this health hazard are included