Report of a rare case of anterior mediastinum goiter

The primary ectopic goiters of mediastinum, specially of posterior mediastinum is rare and estimated on 1% of the goiters of retro sternal and mediastinum and their blood supplies is from intra thoracic vessels. We introduce a patient who referred with the complain of a huge mass in the anterior medistinum. His complain presented by dyspnea breathlessness and chronic cough at first. This mass was removed easily through collar incision and partial strernotomy. Through surgery we found that blood supply of mass arised from thoracic vessels and inominate artery, with drainage to inominate vein. Following mass removal, all the symptoms of the patient were resolved. We presented an uncommon true primary ectopic mediastinal goiter resected through a median strnotomy with complete excision and relief of all symptoms

Synthesis and anticonvulsant activity of novel 2-amino-5-[4-chloro-2-[2-chlorophenoxy] phenyl] -1, 3, 4-thiadiazole derivatives

Several novel 2-amino-5-[4-chloro-2-[2-chlorophenoxy]phenyl]-1, 3, 4-thiadiazole derivatives 4a-d were synthesized and their anticonvulsant activity was determined by evaluation of the ability of theses compounds to protect mice against convulsion induced by a lethal doses of pentylentetrazole [PTZ] and maximal electroshock [MES]. The result of anticonvulsant data shows that among the synthesized compounds, 5-[4-chloro-2-[2-chlorophenoxy]phenyl]-N-ethyl-1, 3, 4-thiadiazol-2-amine 4c was the most active compound in both MES and PTZ tests with an ED[50] of 20.11 and 35.33 mg/kg, respectively

Neurogenic hypertension: report of five cases to highlight the controversy

The entity of "neurogenic hypertension" is defined as arterial hypertension caused explicitly by derangement of the intricate network of the central nervous system. Among 193 cases of cranial rhizopathies operated on between 1984 and 1995 at this center, 5 cases of established arterial hypertension with concomitant rhizopathies also underwent ventrolateral medullary decompression. The elevated blood pressure showed an incredible decline, reaching normal values after vascular decompression. The systolic blood pressure however showed a much greater fall than the diastolic component. An endeavour is made to throw light on the cases operated on with special emphasis on the central nervous system as an etiological factor to explain the cause of essential hypertension