Assessment of diastolic dysfunction in hypertensive patients and its association with left ventricular mass index

Early detection of diastolic dysfunction in hypertensive patients to reduce complications and improve outcome. East Medical and Cardiology wards of Mayo Hospital Lahore. Study A descriptive cross-sectional study. 51 hypertensive patients between 50 - 80 years of either sex enrolled through out patient department of Mayo Hospital Lahore underwent Doppler Echocardigraphy and data was analyzed by using Chi-square and Students 't' tests. The percentage of left ventricular hypertrophy [LVH] was 66.66%. On comparing hypertensive patients with and without LVH, E and A wave velocities, E:A ratio, deceleration time and isovolumic relaxation time were similar. 33.33% of patients had no LVH in the presence of diastolic dysfunction so LVH was not an independent factor associated with abnormal flow patterns in hypertensive patients with normal systolic contractility. Impaired relaxation was the predominant pattern of diastolic dysfunction an d increased further with age

Comparison of lipid profile in thrombotic and haemorrhagic stroke patients

To compare lipid profile in thrombotic and haemorrhagic stroke patients. All general medical and neurology wards of Mayo Hospital Lahore. Study was conducted in 40 consecutive patients of stroke admitted in hospital. Serum lipid [total cholesterol, triglycerides, low density lipoproteins, very low density lipoproteins, high density lipoproteins and LDL/HDL ratio] were estimated in all selected patients within 7 days of onset of stroke and findings were entered on study proforma specifically designed for this purpose and analyzed statistically by students "t" test. Out of 40 patients included in the study, 22[55%] were suffering from thrombotic stroke while 18[45%] suffered from haemorragic stroke. The difference in the values of total cholesterol, triglycerides, low-density lipoproteins, very low density lipoproteins, high density lipoproteins and LDL/HDL ratio was not statistically significant between the two groups of patients. It is concluded that serum lipids i.e., total cholesterol, triglycerides, low density lipoproteins, very low density lipoproteins, high density lipoproteins and LDL/HDL ratio does not have any differential effect in the causation of thrombotic or haemorrhagic strokes

Precipitating factors for diabetic ketoacidosis

The objective of the study is to evaluate different precipitating factors for diabetic ketoacidosis. All medical wards of Mayo Hospital, Lahore. This descriptive study was conducted on 50 patients. Patients and their relatives were selected for interview on the basis of convenient sampling. The data was collected on specially designed proforma. The proforma was filled for each patient. All patients were investigated with various blood tests, urine tests, ECG and chest X-rays. The data analysis was computer based. SPSS 10 was employed for this purpose. The mean age was 31.3 years. 60% of the patients were males. Diabetes mellitus was newly diagnosed at presentation in 22% patients. Vomiting was present in 44% patients. Mean blood sugar level was 509mg/dI [380-98mgIdl]. Mean arterial p1-I value was 7.05 [6.9-7.2]. Infection [56%] and non-insulin compliance [38%] were the most common precipitation factors. Poor knowledge about disease, treatment and follow up was also noted. Infection and poor medication compliance are major precipitating factors for diabetic ketoacidosis. Level of health education is very poor; so more emphasis should be given to the health education of the diabetics