ABSTRACT
Wound healing disorders are probably the most common post-transplantation surgical complications. It is thought that wound healing disturbance occurs due to antiproliferative effects of immunosuppressive drugs. On the other hand, success of transplantation is dependent on immunosuppressive therapies. Antihuman thymocyte globulin [ATG] has been widely used as induction therapy but the impact of this treatment on wound healing is not fully understood. To investigate wound healing complications after ATG therapy in renal transplant recipients. The medical records of 333 kidney transplant recipients were assessed for wound healing disorders. Among these patients, 92 received ATG and 5 doses of 1.5 mg/kg ATG along with the standard protocol of drugs. The mean age of patients was 38.9 years. Of 333 recipients, 92 [23.7%] received ATG; 21 [6.3%] developed wound healing complications. There was a significant relationship between ATG therapy and wound complications [p=0.034]. Also, women were more likely to develop wound healing disorders than men [p=0.002]. No statistical difference was observed between age and wound healing complication [p=0.28]. There was no significant difference between the mean duration of hospitalization between ATG and Non-ATG group [p=0.9]. ATG increases the risk of overall wound complications. It is needed to pay more attention to the patients treated with this immunosuppressant to avoid the risk of re-interventions, lessen the duration of hospitalization and decrease the impairment of graft function
ABSTRACT
Premature contact of teeth in posterior crossbite may be associated with facial asymmetry. To describe the surgical treatment of mandibular deviation associated with a marked facial asymmetry, and build up the two upper lateral incisors in place of the two upper central incisors. A 20 year-old boy with a unilateral posterior crossbite, noticeable facial asymmetry, and anterior crossbite is presented. He had a history of head injury in mixed dentition period. The upper central incisors were lost during trauma and the created space was replaced by the two upper lateral incisors. A removable appliance was used to correct the crossbite and it was followed by fixed appliances. Orthognathic surgery was done to complete the treatment. After that the two upper lateral incisors were built up and reshaped. Treatment resulted in a marked improvement in facial symmetry, elimination of the mandibular displacement and a stable occlusion. A patient with mandibular deviation and marked facial asymmetry was successfully treated surgically and two upper lateral incisors were built up and reshaped in place of the two upper central incisors