Psychomotor delay, a possible rare presentation of moyamoya disease

Moyamoya disease is a rare, chronic cerebrovascular occlusive disease of unknown etiology. It is characterized by progressive stenosis of the arteries of the circle of Willis leading to ischemic strokes in young people and cerebral hemorrhage, which is more frequent in adults. Secondarily, an abnormal network of fine collateral vessels arises at the base of the brain. The term moyamoya refers to the angiographic appearance of the cerebral vasculature. We present such a disease in an 18-month-old Iranian girl with global developmental delay, which is a very rare presentation of moyamoya disease. She was diagnosed by magnetic resonance imaging [MRI] and magnetic resonance angiography [MRA]

[Evaluating complications of pregnancy in patients with hyperemesis gravidarum]

Nausea and vomiting in early stages of pregnancy is a common complaint. In patients with HEG [hyperemesis gravidarum] adverse fetal outcomes, including abortion, preterm delivery, low birth weight [LBW] and maternal outcome [e.g. preeclampsia] are more common than in normal pregnancy. In this study, we evaluate the incidence of some adverse fetal and maternal complications among the patients with HEG. This study was performed on 70 patients [under 14 weeks of gestations] with HEG admitted in Yahya-Nejad hospital [Babol] as the study group and 100 cases referred to prenatal care as the control group. All the patients were followed up until the time of delivery. The incidence of preterm delivery in the HEG and control group was 9.4% and 1%, respectively, considered statistically significant [P=0.015]. The incidence of abortion in the HEG and control group was 8.6% and 1%, respectively, which was significant [P=0.02]. The incidence of gestational diabetes in control and HEG group was 0% and 10.9%, respectively [P=0.001]. There was no significant difference between the study group and the control one in terms of the type of delivery, weight / mortality of neonates and preeclampsia. Considering the high incidence of gestational diabetes, preterm delivery, abortion and morbidity of neonates in patients with HEG, close observation of patients with HEG during the pregnancy is recommended

determination of clinical decision rule for estimation of mineral bone density in Iranian women

Osteoprosis is a well recognized health hazard for women who are the main group at risk.This study assessed the relative risk factors of osteoprosis in women referring to the Chamran Hospital densitometry center during the year 1386, with the aim of designing a formula to estimate the severity of osteoprosis based on its risk factors. This cross sectional analytic study used the data of outpatients [n=1047] who visited the Bone Densitometry Center of Chamran Hospital during the year 1386. Information was gathered using questionnaires, completed face to face and the cases underwent Dexa densitometry of the hip and vertebras. The data were analysed with SPSS software. Results Of the patients, 73% were menopausal the average and standard deviation of age and weight was 54.5 +/- [10.3], 69.5 +/- [10.8] and the average and standard deviation of T-score of hip and lumbar spine was -1.88 +/- [1.08], -1.04 +/- [1.05]. After assessment, the precipitating factors of osteoprosis of hip were age, menopause, time of menopause, history of fracture, history of taking calcium supplements and dosage, number of deliveries, and duration of breast feedings. The preventing factors were weight, OCPs, exercise, [P < 0.05] being significant the percipitating factors in vertebras were age, menopause, time of menopause, diabetes, history of fracture, history of calcium supplement usage and dosage, number of deliveries, timing of breast feeding and the preventing factor was weight, [p=<0.05] being significant. Using the use of stepwise regression analysis, a minimal mathematical model for predicting of bone density of hip and lumbar spine was formulated. Then the mathematical model of hip in the form of clinical decision rule [CDR] was validated with less number of independent cases. Using the method mentioned, along with clinical findings and history, persons at risk of osteoporosis can be identified and early prevention and treatment are possible. This can also prevent unnecessary expenses of diagnostic procedures for people without the risks of osteoprosis