Comparative investigation of the immune response in swiss mice and guinea pigs to brucella vaccine strain 19

Evaluation of Brucella vaccine strain 19 in Swiss mice as an available and economic model in comparison with guinea pigs was done. The results revealed that a good protective antibodies in the sera of vaccinated guinea pigs and Swiss mice, and the level of antibodies still persisted for prolonged period in both animals

effect of different stabilizers on maintainig viability of lyophilized pasteurella multocida strains

In the present study, different stabilizers were used. Results indicated that the best viability percentage [70.60 and 68.00], mean death time in mice, microscopical examination and colonial morphology were shown in lyophilized strains stabilized by skimmed milk lactalbumin sucrose peptone medium and Angus medium respectively, followed by 59% and 58% viability in strains stabilized by skimmed milk, lactalbumin, sucrose medium and skimmed milk peptone sucrose medium respectively