ABSTRACT
The drugs used in Unani Medicine consist of materials from plant, animal and mineral origin that are either used single or in combination with other drugs as poly-pharmaceuticals. Habb-e-Mudir is a poly-ingredient formulation comprising Sibr [Aloe species], Zafran [Crocus sativus] and Hira Kasees [Ferrous Sulphate], in the ratio of 2:1:1 [NFUM I] indicated for the treatment of amenorrhoea. Present study is aimed to standardize the formulation for quality control purpose. Standard sample of the formulation was prepared in laboratory following the NFUM methodology [National Formulary of Unani Medicine]. Separate studies were undertaken for each ingredient in respect of pharmacognostical characters, physico-chemical constituents and HPTLC profile. Standard formulation was subjected to chemical analysis viz. extractive values, ash values, etc. including chromatographic profile in line with standard pharmacopoeial protocols. The results may ensure the quality of Habb-e-Mudir through determining the genuineness and quality of ingredients as well as the manufacturing process
ABSTRACT
Before the advent of modern medicine, the majority of folks relied on the drugs of plant origin for the treatment of common ailments. An appreciable number of these herbal drugs have been scientifically analysed and a lot of them are under such appraisal at present in the research laboratories, however very few attempts have been made to analyse the poly-pharmaceutical preparations especially in the case of Unani Murakkabat [Compound formulations]. Reference may be made to the standardization of Khamira Abresham Hakeem Arshad Wala [Siddiqui, 1964] and the standardization of Jawarish-e-Jalinoos [Israili 1971] and Itrifal Mulayyin [Israili, 1972]. Since the Unani system of medicine uses herbs, animal products as well as minerals, it is necessary to evolve the standards for single as well as poly-pharmaceuticals. To satisfy the present day scientific world it is all the more important to lay down minimum standards of quality and purity for indigenously developed drugs to ensure their uniform effectiveness against disease. In view of these factors an attempt has been made in the present study to standardise constituents of "Itrifal Ustukhuddus," a well-known Unani preparation making use of modern methods of analysis. Itrifal Ustukhuddus is a reputed poly-pharmaceutical preparation of Unani system of medicine. It is extensively used with great success in the treatment of chronic sinusitis, a very common disease causing great discomfort. It is a time-tested drug in Unani system of medicine, and has gained positive reputation due to its wide and divergent actions on different systems of human body. It purifies the body from the waste products and relieves obstruction in the flow of body fluids. It gets rid of toxic substances [metabolites] from major organs like heart, brain, liver, spleen and kidney. It is also useful in epilepsy, melancholia and insomnia [Siddiqui, et al., 1991]. Keeping in view the beneficial effects of Itrifal Ustukhuddus in the nervous and respiratory disorders and its frequency of usage, an attempt has been made to find out the analytical characteristics of this Unani preparation which may prove prelude to fix the chemical standards for this preparation