ABSTRACT
The ability of certain penicillii, isolated from sulfaguanidine spoiled tablets to utilize sulfaguanidine and also sulfanilamide has been investigated. Results showed that sulfaguanidine could be utilized as the only carbon source [but not as the only nitrogen source] when the drug replaced sucrose in Czapek's liquid medium. However, in tablet-fillers liquid medium the drug was utilized as both the carbon and nitrogen sources. Sulfanilamide was only utilized when supplied to tablet fillers liquid medium. In an attempt to eliminate biodeterioration of sulfaganidine by the isolated penicillii, nipagin [propyl paraben was found effective. When this antifungal was applied to the drug tablets and also paper discs, fungal growth was inhibited as shown by Czapek's agar plate assay
Subject(s)
Parabens , Drug Synergism , Chemistry, PharmaceuticalABSTRACT
An attempt has been made to study the distribution of Saprolegnia species in soil and water ody of Nasser's lake. Soil and water samples and plant debris we e collected from, different localities for such a purification of these fungi. Results have shown that certain Saprolegnia species were recorded in Nasser's lake, and they were identified as Saprolegnia type 2
Subject(s)
FungiABSTRACT
An attempt has been made to study the distribution of Allomyces species in some Egyptian soils at Aswan, Asyut, Minya, Beni-Suef, Giza, Cairo, Zagazig, Banha, Tanta and Ismailia. Soil samples were collected from these localities for such a purpose. Sterile boiled hemp seeds were used for isolation and purification of these fungi. Results have shown that certain Allomyces species were recorded in some Egyptian soils, and they are giver, the names Allomyces orbrtsculus, 4. javanicus, A. neo-moniliformis and A. moniliformis