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1.
Pakistan Journal of Pharmacology. 1997; 14 (1): 57-62
in English | IMEMR | ID: emr-46413

ABSTRACT

Nucleic acids [RNA and DNA] contents were estimated in Musca domestica [PCSIR strain] after LD50 treatment of nem compounds [i. e. Margosan [OTM], H - 34, N6 - b] and an organophosphate [DDVP]. RNA and DNA contents were inhibited by all the undertest compounds. Treatment with Margosan - [OTM], H -34 and N6 - b resulted in the inhibition of RNA content upto 23.37%, 23.55% and 33.32% respectively. Whereas the organophosphate, DDVP decreased the RNA content upto 9.67% The effectiveness of the compounds for inhibiting RNA contents may be summarized as follows DDVP < Margosan - O[TM] < H -34 < N6-b. DNA contents also decreased by all the compounds. Inhibition was 19.49% by Margosan - OTM 35.52% by H - 34; 25.02% by N - 6 - b, and 28.82% by DDVP. The effectiveness of the compounds for inhibiting DNA contents may be summarized as follows. Margosan- O[TM]

Subject(s)
Insecta , Houseflies/drug effects , Dichlorvos/pharmacology , Organophosphorus Compounds , Cholinesterase Reactivators/pharmacology
2.
Pakistan Journal of Pharmacology. 1994; 11 (2): 41-4
in English | IMEMR | ID: emr-35098

ABSTRACT

The effect of LD50 treatment of NC and Solfac [cyfluthrin] on the whole body nucleic acids of adult Musca domestica L. [PCSIR strain] revealed 30.23% and 19.30% inhibition of RNA and DNA by NC and 17.70% and 15.63% by Solfac, respectively


Subject(s)
Nucleic Acids/drug effects
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