[Antimicrobial effect of zataria multiflora and rosemarinus officinalis on antibiotic-resistant staphylococcus aureus strains isolated from food]

Staphylococcus aureuse is one of the important pathogens which transmitted by food and has majority of habitant in human and animal community as a pathogen and normal flora. Antibiotic resistant among Staphylococcus aureuse strains is a global health challenge. Regarding to the different therapeutic and antimicrobial effect of Shirazi Zataria multiflora and Rosemarinus officonalis in present work the antibacterial effect of this extract and its synergistic effect with routine antibiotics was investigated. In this in vitro study the antimicrobial effect of Shirazi Zataria multiflora and Rosemarinus officonalis extract on methicillin resistant Staphylococcus aureus [MRSA] and other antibiotic resistant strains to tetracycline, erithromycine, trimethoprim, sulfamethoxazol, together with its MIC and MBC were determined. Also synergistic effect of these extracts with these antibiotics was investigated by paper disc method. Shirazi zataria multiflora, had a significant antibacterial effect against MRSA, and other Staphylococcus aureus resistant strain to tetracycline, erithromycine, trimethoprim, and sulfametoxazol, isolated from food. Production of a suitable herbal medicine with few side effects will give rise to a promising outlook in the treatment of infections caused by antibiotic resistant strains of Staphylococcus aureus

effect of rehabilitation program on lymphedema- related arm pain, and volume after mastectomy

Upper extremity Lymph edema is the most common complication after mastectomy. The aim of this study is determining the effect of home based rehabilitation program on lymph edema related arm pain and arm volume after mastectomy among breast cancer survivors. In this quasi-experimental [before- after design], 16 post - mastectomy women with mild lymphedema [

[Role of tumor markers in breast cancer recurrence]

Introduction: The value of clinical use of tumor markers for prediction of breast cancer recurrence in follow-up or level of response to treatment is still controversial

Objective: In this study, the role of tumor markers in breast cancer recurrence was evaluated

Materials and Methods: One hundred and forty-one breast cancer patients were entered into the study and followed up for 132 months [mean= 34.0, SD= 28.0]. The mean age of the patients at time of diagnosis was 47.1 [SD= 12.3] ranging from 23 to 81 years. Most patients [51%] were presented with stage II breast cancer. 81% of the patients underwent modified radical mastectomy and the remaining 19% had breast preservation surgery. The association between clinical recurrence with age, tumor size, nodal involvement, stage, type of surgery and pathology, CA15.3, CEA, P53, ER, PR, and HRE-2 status were examined by using the forward conditional logistic regression analysis

Results: Recurrence occurred in 22% of patients during the follow up time. The results indicated that recurrence was significantly predicted by the status of CA15.3 [odds ratio= 6.1, 95% CI= 1.62-23.1, P= 0.007]

Conclusion: The findings showed that independent of age and other known prognostic factors CA 15.3 is an individual factor for prediction of recurrence in breast cancer patients