ABSTRACT
Background: ribes biebersteinii [Rb] is one of pharmaceutical plants which was used in traditional medicine for decreasing blood sugar
Objective: in this study, effect of aqueous fruit extract of Rb on blood sugar of rats was Investigated
Methods: in this research 60 male Wistar rats were categorized randomly in 10 equal groups with two timeframes [7 and 14 days]. Extraction of Rb was performed with 50 g in 500 ml of distilled water for 18 hours by using a soxhlet extractor. For inducing diabetes, streptozotocin 7 mg/0.5 ml in normal saline was injected intramuscularly per 100 gram of rat body weight. Aqueous fruit extract of Rb was given orally to rats daily [80 mg/0.5 ml in distilled water per 100 gram of rat body weight]. Then the blood samples sent to the laboratory to measure the following factors: glucose, lipids; and activity of the enzymes in plasma serum
Results: ribes biebersteinii compared to diabetic group had significant effect on blood sugar [P
Conclusion: according to the results concluded that extract of Ribes biebersteinii had effect on the blood sugar of rats and led to decrease blood sugar of rats. Because the fruit is rich in anthocyanins, this effect may be due to the antioxidant effect
ABSTRACT
Polycystic ovary syndrome [PCOS] is one of the most prevalent endocrine disorders in reproductive age and is also considered as the most popular cause of infertility due to lack of ovary release. On the other hand, present condition of high expenses of infertility treatment and midwifery science slogan as "deliver a healthy infant to a healthy mother" all reflect the necessity to take care of these patients and to check their pregnancy stages precisely. This study aimed to investigate the pregnancy complications among patients with polycystic ovary syndrome. This was an analytic prospective cohort study. The population studied comprised all Iranian nullipars women with pregnancy of one quite healthy fetus. They were divided into two groups including 47 subjects with PCOS and 100 subjects with no PCOS. Pregnancy and delivery complications such as pregnancy sweat, diabetes, eclampsy and early delivery were recorded. The data were collected through interview and analyzed by descriptive inferential statistics through SPSS . The findings of the study showed that the rates of abnormalities in screening tests of diabetes, pregnancy diabetes and eclampsy in pregnant women with PCOS were more than those in controls but there was no significant difference between the two groups in early delivery. Since obesity seems to be the major cause of diabetes and eclampsy in patients with PCOS, these patients need critical care during pregnancy and screen them properly for diabetes and eclampsy