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Rev. cuba. med. trop ; 64(1): 65-68, ene.-abr. 2012.
Article in Spanish | LILACS | ID: lil-615582

ABSTRACT

Introducción: las manifestaciones clínicas por brucelosis han sido muy poco investigadas y no se profundiza en los síntomas y las posibles complicaciones que puede causar. Objetivo: reportar por primera vez en Cuba un caso de endocarditis infecciosa a consecuencia de brucelosis. Métodos: hombre blanco, de 57 años, campesino, remitido desde Vertientes, que ingresó en diciembre de 2009 en el Hospital Provincial "Manuel Ascunce Domenech" de Camagüey, con diagnóstico presuntivo de endocarditis infecciosa por Brucella e insuficiencia aórtica moderada, que refirió presentar fiebre, malestar general, decaimiento, dolores musculares, articulares, artritis, astenia marcada, anorexia, signos neurológicos, sudoración y fuerte dolor en el pecho. En anteriores ingresos fue tratado con antimicrobianos, indicándole entre los complementarios, serología lenta en busca de brucelosis, pero por no disponibilidad de reactivos no se realizaron estas pruebas hasta enero de 2010. Se precisaron como antecedentes epidemiológicos el contacto directo con ganado vacuno y porcino y la presencia de heridas y microtraumatismos en manos y pies, propios de su labor. Su finca colinda con otra donde hay ganado afectado de brucelosis. Resultados: los exámenes de laboratorio resultaron positivos con elevados títulos serológicos, y aunque no fue posible el aislamiento del agente etiológico mediante el cultivo, se confirmó serológicamente la enfermedad y la endocarditis infecciosa como complicación sobreañadida; esto llevó tratamiento con antimicrobianos y medicamentos para la afección cardíaca. Se diagnostican muy poco estas complicaciones a consecuencia de brucelosis en la literatura internacional, este es el primer reporte para Cuba. Conclusiones: la descripción de este caso, constituye una alerta en el diagnóstico de las endocarditis infecciosas quizá asociadas a antecedentes epidemiológicos de brucelosis.


Introduction: the clinical manifestations of brucellosis have been poorly researched on and the symptoms and possible complications have not been deeply studied either. Objective: to report a case of infective endocarditis caused by brucellosis for the first time in Cuba. Methods: a Caucasian male farmer aged 57 years was referred from Vertientes municipality to be admitted at "Manuel Ascunce Domenech" provincial hospital in Camaguey province in December,2009. He had been presumptively diagnosed with infectious endocarditis caused by Brucella and with moderate aortic failure since he presented with fever, general malaise, fatigue, muscle and joint pains, arthritis, marked asthenia, anorexia, neurological signs, sweating and strong chest pain. In his previous hospitalization, he had been treated with antimicrobials after indication of supplementary tests such as slow serology for brucellosis; however, specific reagents were not available,so these tests were not performed until January 2010.The epidemiological history of this case included his direct contact with cows and pigs as well as wounds and minor traumas inflicted on his hands and feet resulting from his type of work. His farm is next to another farm where the cattle is also affected with brucellosis. Results: the lab tests were positive with high serological titres, and although it was not possible to isolate the etiologic agent through culturing, the disease and the infective endocarditis were serologically confirmed as additional complication; this required antimicrobial treatment and drugs for the heart disease. These complications from brucellosis are barely diagnosed in the international literature, and in Cuba, this is the first report of the disease. Conclusions: the description of this case is an alert to diagnosis of infective endocarditis that may be associated with epidemiological history of brucellosis.


Subject(s)
Humans , Male , Middle Aged , Brucellosis , Endocarditis, Bacterial/microbiology , Cuba
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