ABSTRACT
To determine the most chromosomal abnormalities seen in Childhood Acute Lymphoblastic Leukemia [CALL] in Mosul, and to evaluate the correlations between clinical haematological and chromosomal abnormalities in CALL. Clinical notes, haematological parameters and cytogenetic analysis were studied for all patients. Cases were collected from oncology unit at Ibn Al-Atheer Teaching Hospital [ATH] in Mosul. The frequency of normal karyotype was [42.9%] while the frequency of pseudodiploidy, hyperdiploidy and hypodiploidy were [8.5%], [28.6%] and [20%], respectively. Cases with hyperdiploidy had significantly low Total Leukocyte Count [TLC], higher platelet count with [P<0.001], [P<0.05], respectively. Massive Hepato-Splenomegaly [MHS] was seen mainly in hypodiploidy group [P<0.01]. Normal karyotype was commonly seen in CALL in Mosul followed by hyperdiploidy. Good prognostic parameters were mainly seen in cases with hyperdiploidy