ABSTRACT
To document the profile of patients with colorectal cancer, modes of management and outcome. Cross sectional prospective study. This study was conducted at DUHS and CHK Pakistan from July 2007 to June 2012. Diagnosis was confirmed on histopathology through procto-sigmoidoscopy and colonoscopic biopsy. Abdominal ultrasounds and CT scan were used to stage the disease. Treatment was planned according to the presentation. Surgical procedure was decided according to the site and stage of the tumor. Neoadjuvant chemo-radiation was given for advance and adjuvant therapy for early tumors. A total of 72 patients were included in the study. Majority of patients [n=29 - 40%] presented with advance disease [stage IV]. Carcinoma rectum was diagnosed in 40 [55.5%] cases, sigmoid colon carcinoma in 12[16.6%], caecal cancer in 10[13.8%], ascending colon [n=6 - 8.3%], transverse colon and anal canal [n=2-2.7%] each. Anterior resection [APR] was performed in 20 [27.7%] cases, low anterior resection in two [2.7%], abdomino perineal resection in eight [11%], laparoscopic assisted APR in two [2.7%], Hartmann procedure and only stoma formation in ten [13.8%] each. Histopathology confirmed poorly differentiated adenocarcinoma in 36 [50%] patients. Overall mortality was 9.7% [n=7]. Majority of the patients diagnosed with carcinoma rectum were young and presented with advance disease