ABSTRACT
Background: Acute Kidney Injury (AKI) is a strong predictor of in-hospital adverse outcomes, which is a common complication of acute coronary syndromes (ACS). ACS patients with renal impairment during hospitalization are associated with adverse outcomes like heart failure, cardiogenic shock, arrhythmia, dialysis requirement and mortality. Objective: To compare ACS patients with or without AKI has significant risk of in-hospital adverse outcomes. Methods: This prospective comparative study was conducted in the Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, during the period of July 2017 to June 2018. A total of 70 eligible patients were included in this study. Electrocardiography, blood test for serum creatinine (on admission, 12 hours, 48 hours and at the time of discharge), lipid profile, RBS, 2-D echocardiography along with serum troponin, CK MB and electrolytes were done for all patients. Results: It was observed that mean age was 58.0±8.5 years in group A (ACS with AKI) and 55.6±12.3 years in group B (ACS without AKI). Male population was predominant in both the groups (85.7% and 74.2%, respectively). Heart failure was more common in group A than in Group B (74.3% vs 34.2% p=0.001 respectively). Arrhythmia was more common in group A than in Group B (100% vs 74.2% respectively). The mean duration of hospital stay was significantly higher in Group A than in the Group B (9.4±2.3 vs 7.2±0.6; p=0.001) days. Conclusion: This study showed adverse outcomes including longer duration of hospital stays were more common in the patients with AKI (group A) than in the patients without AKI (group B).
ABSTRACT
Ovulatory dysfunction is a group of disorders with variable clinical presentations occasionally having serious long-term adverse effects. It accounts for 30% of female fertility problems. Evidence suggests an association between an individual's weight and disorders of ovulation. The objective of our study was to describe the clinical and hormonal profile of subfertile women with ovulatory dysfunction in relation to their body mass index [BMI]. This prospective, descriptive study was carried out in Mother and Child Health Centre, PIMS, Islamabad and railway hospital, Rawalpindi from April 2001 to March 2007. One hundred and thirty eight infertile patients with ovulatory dysfunction were included. The clinical data including BMI of each patient was recorded in addition to reports of investigations comprised of cervical smear, pelvic ultrasound and hormonal profile. Primary infertility was found in 61% while secondary in 39% of the patients. The mean age was 29 years and mean duration of infertility was 6 years. Menstrual pattern was normal in 56.5%. BMI was normal in 30.4% while most patients were overweight and obese. Prolonged cycles, history of systemic endocrine disorders, abnormal vaginal -discharge, hirsutism, polycystic ovarian morphology and hormonal abnormalities are more frequent in overweight than infertile patients with ovulatory dysfunction having a normal BMI