ABSTRACT
To investigate blood glucose regulaitng effects of Catharanthus Roseus [C.roseus] and Nigella sativa [N.sativa] in alloxan induced diabetic rats. Experimental study. Animal house Isra University Hyderabad. From April to Novermber 2013. 50 male rats were housed at normal température, 12 hour dark - light cycle with free access to chow and water. A single intraperitoneal bolus of alloxan [120 mg/kg] was given to induce diabetes mellitus. Glimepiride, C. roseus and N. Sativa were administered at doses of 0.1 mg/kg, 125 mg/kg and 50 g/kg respectively. Data was analyzed on SPSS version 21.0. Significant P - value was defined at