ABSTRACT
Purpose@#To report our experience of fertility preservation (FP) in female cancer patients. @*Materials and Methods@#We retrospectively analyzed the medical records of female who underwent elective oocyte or embryo cryopreservation before cancer treatment between January 2015 and December 2020 at Asan Medical Center. We analyzed the type of cancer, the rate of reuse of cryopreserved oocytes or embryos, and fertility outcomes such as the resumption of menstruation or pregnancy. @*Results@#A total of 174 patients underwent 182 oocyte retrieval cycles after controlled ovarian stimulation for oocyte or embryo cryopreservation. The median age of patients was 33.0 (range 19–46) years, and the patients were most unmarried female (65.52%). The majority of patients were diagnosed with breast cancer (78.16%), and the remaining were diagnosed with gastrointestinal (6.33%) and hematologic malignancies (5.75%). The maturation rate of oocyte cryopreservation was 83.33%, and the fertilization rate of embryo cryopreservation was 72.07%. Of the 57 patients currently not undergoing cancer treatment, 34 resumed menstruating and 19 (33.33%, 19/57) returned to attempt a pregnancy. Among them, five patients succeeded in natural pregnancy.Eleven patients received frozen-thawed embryo transfer, and four patients succeeded in becoming pregnant (36.36%, 4/11). Only 6.3% of patients returned to use their gametes, and 93.7% of gametes are still in storage. @*Conclusion@#FP in cancer patients should be considered before cancer treatment. Through continuous research on oncofertility, it is necessary to consider how to increase the return rate and provide appropriate information to cancer patients of reproductive age.
ABSTRACT
Background: Acute appendicitis is the most common abdominal surgical emergency in adults as well as children.Due to the peculiar anatomy of the appendix in children and the unique characteristics of this age group, acuteappendicitis frequently presents atypically, more frequently misdiagnosed, and thus should be differentlyapproached. Objective: Our aim was discussing the unique features of the appendix and acute appendicitis inchildren, and how it’s approached and managed. Methods: We searched Pubmed for acute appendicitis, children,anatomy, manifestation, diagnosis, and management. Conclusion: Acute appendicitis in the pediatric age grouphas several peculiarities when compared to adults. It frequently presents atypically, and therefore more commonlymisdiagnosed. An algorithmic approach that integrates a clinical scoring system, such as the PediatricAppendicitis Score and diagnostic studies should be followed. Moreover, when surgery is decided, thelaparoscopic approach is the standard of treatment and should be always used unless contraindicated. In brief,acute appendicitis in children is not just a smaller appendix inflamed.
ABSTRACT
Background: Sickle-cell disease [SCD] is a group of genetic disorders characterized by abnormally shaped red blood cells [RBCs], which are destroyed at increased rates, leading to anemia. Recently, Saudi Arabia has been reported to have an increased prevalence of SCD
Objective: The aim of the present study was to assess perceptions about SCD among the general population in Albaha region, Saudi Arabia, and the possible relationship between their levels of knowledge and sociodemographic characteristics
Methods: The study was carried out on 218 Saudi subjects who completed the selfadministered questionnaires during the study period
Results: This study demonstrated that more than two-thirds of the respondents [68.80%] had good knowledge about basics of sickle cell disease. Those with poor knowledge [31.20%] were mainly younger males and works as businessmen and housewives, and all of them had no previous experience with SCD child. Despite the recorded favorable level of knowledge, certain gaps in knowledge were identified; most of them falsely believed that some foods like fava beans, lentils, falafel made with fava beans, vigna and /or nuts could precipitate sickle-cell crisis.Moreover, in depth information of our study population about pattern of inheritance of SCD and its complications were not sufficient
Conclusion: In our study, a good level of awareness regarding SCD was found. Some of the respondents were confused about the nature of inheritance, complications and dietary factors related to the disease. So, community health education meetings and/or media programs to increase the public awareness are recommended
ABSTRACT
Introduction: divorce has been a serious problem of major prevalence in our community. According to Saudi Ministry of Justice, divorce rate was estimated to be 27.84% in 2015. Therefore, this study aimed to obtain the incidence of divorce among cancer patients in Princess Noura Oncology Center to know whether being diagnosed with cancer would affect the marital status in terms of divorce
Patients and Methods: the study included 125 patients with age of 15-70 years, have been married, and diagnosed with cancer. Patients were interviewed in the clinic. For data analysis, we used SPSS. Institutional Review Board approval was obtained
Results: divorce rate among cancer patients was significantly lower than that of the general population [P value <0.001]. It was found to be higher in patients with breast cancer 50%, followed by non-solid tumor 33% of all divorces. 66% of divorced cancer patients were females
Conclusion: divorce rate in cancer patients is lower than that of the general population. Therefore, we believe that cancer has led to stronger relationships. Cancer by itself does not increase the rate of divorce. Interestingly, it is generally found to be higher in female patients and breast cancer
ABSTRACT
In spite of being rare, fat embolism syndrome is considered a fatal complication after bone fracture and orthopedic procedures. It was suggested that early immobilization might reduce the incidence of fat embolism syndrome. However, no enough data are available to justify this finding
Objectives: The aim of this review is to determine the incidence of fat embolism among patients who had long fracture fixation
Methods: A systematic review of Medline and Cochrane library was conducted on their database. This search yielded 34 papers, 13 of which were related
Results: The incidence of fat embolism syndrome after long fracture fixation ranged from 2.7% and 11%. More specifically, the incidence among long bone fracture patients who were operated early [within the first 24 hours after injury] ranged from zero% in some studies [16,19] to 1.8% in others. As regards late operation, after 24 hour of bone fracture, the incidence of fat embolism syndrome [FES] ranged from 3.5% to 10.4
Conclusions: The incidence of fat embolism in post long fracture fixation is very low. Several research works indicate that early fixation significantly reduce the incidence of FES compared to late fixation