ABSTRACT
Thymoquinone (TQ), one of the active components of Nigella sativa exhibited to have many biological effects. Several beneficial effects of TQ such as its antidiabetic, antioxidant, anticancer, hypolipidemic, and anti-inflammatory activities have been recognized. The present review focuses on the findings of recent studies on the protective effects of TQ against cardiovascular diseases. In the current review, we additionally concluded that TQ may be therapeutically effective agents for controlling diabetes and hyperlipidemia by decreasing the oxidative stress and inflammatory responses.
ABSTRACT
Thymoquinone (TQ), one of the active components of Nigella sativa exhibited to have many biological effects. Several beneficial effects of TQ such as its antidiabetic, antioxidant, anticancer, hypolipidemic, and anti-inflammatory activities have been recognized. The present review focuses on the findings of recent studies on the protective effects of TQ against cardiovascular diseases. In the current review, we additionally concluded that TQ may be therapeutically effective agents for controlling diabetes and hyperlipidemia by decreasing the oxidative stress and inflammatory responses.
ABSTRACT
Curcumin (CUR), the main phenolic composition in turmeric, shows preventive effects in various diseases. CUR is commonly found in the Curcuma species and historically applied in herbal medicine. Numerous studies have indicated that CUR possesses protective effects against toxic agents in the various animal tissues including the brain. This study found that CUR may be effective in nervous system problems induced by neurotoxic agents. However, due to the lack of information on human, more investigations are needed to determine the efficacy of CUR as an antidote matter. The current study aimed to critically review the recent literature data from 2014 to 2016 that regarding the therapeutic aspects of CUR versus neurotoxic agents-induced brain damage and its involved mechanisms.
ABSTRACT
Curcumin (CUR), the main phenolic composition in turmeric, shows preventive effects in various diseases. CUR is commonly found in the Curcuma species and historically applied in herbal medicine. Numerous studies have indicated that CUR possesses protective effects against toxic agents in the various animal tissues including the brain. This study found that CUR may be effective in nervous system problems induced by neurotoxic agents. However, due to the lack of information on human, more investigations are needed to determine the efficacy of CUR as an antidote matter. The current study aimed to critically review the recent literature data from 2014 to 2016 that regarding the therapeutic aspects of CUR versus neurotoxic agents-induced brain damage and its involved mechanisms.
ABSTRACT
Introduction and Aims: despite the restrictions for the use of lead-containing compounds in industry and services, it remains one of the main agents to create acute and chronic poisoning, particularly in industrialized countries in the world
Materials and Methods: we searched all published articles from 1980 to 2014 by using of web search engine such as ISI Web of Science, Science direct, PubMed and Scholar Google
Results: several epidemiological studies indicate a possible role of this metal in exacerbation of asthma. Despite the development of therapeutic strategies for asthma and chronic obstructive pulmonary disease in humans and animals, the disease has not subsided and remains a serious threat for human and animal health. Finding of the etiologic relationship between these diseases and intoxications occupational, environmental, and sustainability-environmental could be replaced progress therapeutic approaches with an advanced proactive approach to achieve substantial progress. A present review study has been conducted to investigate the experimental and epidemiological studies the effects of lead exposure on the occurrence of theattack of asthma
Conclusion: the results indicate that lead may cause increased airways responsiveness, pathological changes and inflammatory responses in victim
ABSTRACT
Several diseases are reported to be uncommon in those parts of the world where dietary fiber intakes are high, therefore, in this study; we evaluated the hypocholesterolemic effects of a dietary fiber [guar gum] in hypercholesteromic rats. Rats were fed high-fat or a normal fed diet for 12-week then treated with 5% guar gum in their regime during a 28 days period. Total cholesterol was significantly increased in high-fat diet rats, while administration of guar gum significantly lowered it. Body weight was significantly increased in high-fat diet rats while, at the end of 4-weeks treatment of guar gum, body weight of treated rats was significantly decreased. These results suggested that guar gum may be effective as hypocholesterolemic agent and may prevent hypercholesteromia in hypercholesteromic rats. The results also suggested that guar gum may be important for reducing body weight in hyperlipidemic rats