ABSTRACT
To determine the sensitivity and specificity of Cornell product index for left ventricular hypertrophy with reference to echocardiography. Descriptive study. Medical Unit 111, Jinnah Post-graduate Medical Centre Karachi. June 1998- February 1999. 50 patients with echocardiographic left ventricular hypertrophy [LVH] and 25 normal healthy persons without echocardiographic LVH were included in this study. All patients and control subjects were examined clinically and their ECGs were taken on that same day. Echo LVH was defined if Left Ventricular Mass Index exceeded 118 g/m2 in males and 104 g/m2 in females. Data was preserved and now it is analyzed for Electrocardiographic LVH in view of Cornell voltage and Cornell product index. Sensitivity and specificity was calculated by standard formula and P value derived by chi square test. 50 patients which were included in the study, 21[42%] were male and 29 [58%] were females; while 25 healthy persons without LVH, 12 [48%] were males and 13 [52%] were females. Cornell voltage criterion was having sensitivity of 48% as over-all, 48% in males and also 48% in females. It was 96% specific. Cornell product index was the higher sensitive criteria by scoringing 57% in males, 62% in females and 60% in all patients. Although electrocardiography is less sensitive than echocardiography, but can perform better in certain groups and with improved criterion. Cornell product criterion has the highest sensitivity as compared to other criteria
ABSTRACT
To determine the proportion of Diabetes Mellitus [DM] in patients with documented first episode of Acute Myocardial Infarction [AMI], in both genders. A prospective, case control observational study. Emergency Room, CCU and Medical wards of Chandka Medical College Hospital Larkana, Pakistan, from January 2005 to August 2005. 200 patients 100 consecutive males and 100 consecutive females, presenting with definite first episode of AMI. Diagnosis of D.M established on previous history of D.M, medical record and medications used by patient, patients without previous diagnosis of D.M [Undiagnosed], were diagnosed by performing Fasting Plasma Glucose [FPG], once within around 72 hours and 8 weeks later on. Out of 200 patients 49 [24.5%] were known diabetics, 20 [10%] revealed hyperglycemia [suspected diabetics] on routine plasma glucose level and Fasting Plasma Glucose [FPG] petformed within 72 hours of the onset of AMI and on subsequent follow up after 8 weeks, FPG level performed revealed 12 [6%] newly diagnosed definitive diabetics, while 5 [2.5%] revealed Impaired Glucose Tolerance Test [GTT] and 3 [1.5%] were found to be non-diabetics, so that a total 61 [30.5%] were labeled as diabetics. one out of every three patients with AMI had DM, elevated levels of random blood glucose and FPG at the time of admission are not reliable measures to establish the diagnosis of diabetes in cases of AMI and thus follow up measurements after a period of 6-8 weeks are necessary to establish the diagnosis. Awareness in general public regarding deleterious effects of DM should be promoted