ABSTRACT
Head and neck squamous cell carcinoma (HNSCC) stand at the sixth position most, amongst all the malignancies worldwide. Neoplasms arising in the oral cavity, larynx, pharynx, salivary gland and nasal cavity are all included in the head and neck malignancies. More than 90% of malignancies of the oral cavity are squamous cell carcinomas (SCC). Among the four head neck cancer sub-sites combined, the mean age at the time of diagnosis has risen, in the last four decades. Studies have documented a male predilection. A small percentage of SCC cases are inherited or are familial. Cigarette smoking, alcohol consumption, betel quid chewing, poor nutrition, poor oral hygiene, HPV, Epstein-Barr virus and Candida albicans infections are the etiological agents who have the ability to cause HNSCC. Non healing ulcer, difficulty in swallowing, change in voice, swelling, sore throat- that doesn’t get better- are the symptoms of head and neck cancers. Moreover, there may be unusual bleeding, facial swelling or difficulty in breathing.
ABSTRACT
Iodoformized zinc oxide-eugenol was tested for its antibacterial effect against the aerobic and anaerobic bacteria obtained from the root canals of deciduous teeth; the bacteria were staph aureus, strep viridans, strep faecalis, bacteroides melaninogenicus and also mixed culture obtained from infected non-vital anterior teeth. The sensitivity was checked on BHI- agar plates employing well-method. Iodoformized zinc oxide eugenol paste was found to be effective for both the aerobic and anaerobic bacteria of the root canals of deciduous teeth with maximum sustaining period of 10 days; staphylococcus aureus was found to be the most susceptible, while Streptococcus faecalis the most resistant.