ABSTRACT
Change from quadruped to erect posture has resulted in changes in the human pelvis. This has resulted in pelvis supporting the abdominal viscera. The bony pelvis is deficient on inferior aspect. Muscles covered by fascia on superior and inferior aspect. A good knowledge of pelvic floor is very basic and mandatory for any gynecologist as pelvic floor is crucial to support the pelvic organs and is required to maintain urinary and fecal continence.
ABSTRACT
To evaluate the effects of topical timolol on lipid profile, blood samples from 25 patients (16 males and 9 females) were analysed before topical instillation of 0.5% timolol maleate and thereafter at one month and two months. After two months of therapy, the level of high density lipoprotein (HDL) decreased significantly (p < 0.02). The levels of low density lipoprotein (LDL), very low density lipoprotein (VLDL) and triglyceride increased but the changes were not statistically significant. Since low level of HDL is strongly associated with increased risk of myocardial infarction, our study cautions use of topical timolol in patients with low levels of HDL or with previous history of coronary heart disease.
Subject(s)
Administration, Topical , Adrenergic beta-Antagonists/administration & dosage , Adult , Cholesterol, HDL/blood , Cholesterol, LDL/blood , Cholesterol, VLDL/blood , Female , Humans , Lipids/blood , Male , Middle Aged , Ophthalmic Solutions , Timolol/administration & dosage , Triglycerides/bloodABSTRACT
Infective larvae (L3) of Dirofilaria immitis were cultivated in various synthetic media. L3 obtained from Aedes aegypti mosquitoes by mass dissection were inoculated into the media, viz: RPMI 1640 medium with 10 per cent human AB serum (medium-A); Tc-199 medium with organic acids, sugars of Grace's insect medium and 10 per cent foetal calf serum (FCS) (medium-B); and Grace's insect medium with 10 per cent FCS (medium-C). Maximum survival of 26 days was found in medium 'A'. Approximately 80 per cent healthy larvae moulted after 72 hours. They increased in size from an initial average length of 1050 microns and 25 microns width to an average 1600 microns length and 35 microns width. Blunting and rounding of anterior ends were conspicuous.