ABSTRACT
Many herbal medicines have been recommended for the treatment of diabetes. The antidiabetic effect of date pits powder and date pollen grains powder investigated in normal and Alloxan -induced diabetic rats. The rats were divided into 4 groups, first group as normal rats, 2 as diabetic rats without treatment, 3 fed on 25% of date pits powder and 4 fed on 2% of date pollen grains powder. The nutritional experiment was continued for 45 days. Blood samples of non-diabetic and diabetic rats were collected, after 3 days, 15 days and 45 days from administration of Alloxan where serum glucose change were estimated. Other biochemical assays were estimated after 3 days and 45 days only. The results show that the basal diet supplemented by date pits powder and date pollen grains powder induced a decrease in serum glucose, total cholesterol, triglycerides and total lipids and increase in urea and creatinine. The basal diet supplemented with date pits powder or date pollen grains powder showed decrease in weights of liver, kidney and pancreas. While, it showed increase in heart weight. The results from histopathology show no changes in kidney, heart, spleen and pancreas. But, the liver in experimental rats fed on 2% date pollen grains powder showed no change except activation of kupffer cells
Subject(s)
Animals, Laboratory , Animals , Cycas , Plant Proteins , Rats , Anticholesteremic Agents , Blood Glucose , Liver/pathology , Kidney/pathology , Heart/pathology , HistologyABSTRACT
Mixed bee pollens were collected from fields cultivated by sunflower, palm and oxeye daisy plants at Fayoum governorate. The gross chemical composition and the profiles of amino acids and minerals of bee collected mixed pollens were determined. Nutritional experiments were preformed on adult and elderly female rats fed on basal diet and orally supplemented by mixed bee pollen at 2% and 4% levels. Blood samples of adults and elderly female rats were collected at start and after 10, 20, and 30 days of the experiments. Serum total lipids, high-density lipoproteins, triglycerides, total lipids, progesterone and calcium levels were estimated for both adults and elderly female rats. At the end of the experiment, the adult and elderly female rats were allowed to mate and the numbers of fetuses in both cases were counted. The basal diet supplemented with mixed bee pollen induced a lowering lipid effect, increased HDL-cholesterol, progesterone, calcium levels and fertility of elderly female rats