ABSTRACT
Background: Little evidence is available regarding the effects of long-term periodontal infection on diabetes control The aim of this study was to evaluate the influence of periodontal status on changes of glycated hemoglobin (HbA1c) levels of type 2 diabetics Materials and methods: 30 Patients (35 years or older) with type 2 diabetes were included Patients were non-smokers, and were under use of anti-diabetic drugs Demographics, health history and HbA1c levels were retrieved from medical charts Probing depth (PD) and relative attachment loss (AL) were recorded at baseline and after 3 months Results: The level of HbA1c was found to positively correlate with the severity of periodontitis In case of patients with severe periodontitis it was seen that there was a concomitant increase in Hba1c level at 3 month recall Conclusion: The progression of periodontitis was associated with increases in HbA1c in type 2 diabetics The identification of these risk factor suggests that periodontal treatment may improve glycemic control of type 2diabetic patients by eliminating periodontal infection
ABSTRACT
Background: The present clinical trial was designed to evaluate the effects of bioactive glass in treatment of periodontal intra-bony defects. Methods: 25 patients 23-55 years of age with intra-bony defects completed 1 year study. After completion of initial therapy, defects were randomly assigned to either a test or control procedure. Following flap reflection root planning and removal of chronic inflammatory tissue in both groups test defects were restored with bioactive glass, while open flap debridement was done in control sites. Muco-periosteal flaps were replaced sutured and periodontal dressing was used. Follow up was carried out weekly, 3 months 9 months and 1 year post surgery. Plaque score, sulcus bleeding score probing pocket depth were recorded at baseline, 3 months and 1 year. Standardized radiographs using RVG was taken at baseline, immediately post operatively and at 1 year. Results: Radiographs showed a significant increase in radiographic density and volume between defects treated with bioglass when compared with open flap debridement alone. Probing pocket depth, probing attachment level showed improvement in test and control site with greater trend to improvement in test site. Conclusion: It was concluded that bioglass is effective as an adjunct to conventional surgery in treatment of intra-bony defects.