ABSTRACT
Background and Objectives: Deaths from cardiovascular diseases following chronic kidney diseases are rising widely. The aim of this study was to evaluate the efficacy of a combined regular exercise during dialysis on intervening risk factors for vascular calcification diseases
Materials and Methods: Forty-five selected hemodialysis patients with a mean age of 61 +/- 9.02 years weighing 69 +/- 11.25 kg, were randomly assigned to the exercise [n=24] and control [n=21] groups. The exercise group participated in a 16-week combined exercise program. Training program included foot pedal ergometer and foot resistance exercises using weights during dialysis sessions three times a week. Parameters associated with calcification and renal function [FGF23, PTH, P and Ca] and quality of life were measured before and after the training program period
Results: Following four months combined training, parathyroid hormone and phosphorus levels significantly reduced. There were not any significant changes in blood fibroblast growth factor 23 and calcium levels. Also, exercise significantly improved the quality of life and physical functions in hemodialysis patients
Conclusion: Physical activity in hemodialysis patients is associated with changes in some factors related to vascular calcification and also improvement in the quality of life
ABSTRACT
Vaspin is a new discovered adipocytokine which is a member of serine protease inhibitor family secreted from adipose tissue and might play a role in insulin sensitivity. The purpose of this study was to investigate the effect of acute exercise on serum vaspin levels and its relation to insulin sensitivity in overweight elderly men. In this semi-experimental study, 12 healthy elderly men volunteers randomly selected and performed one session aerobic exercise including 30 minutes of cycling at 70-75% of HRmax, which was followed by 30 minutes of recovery. Three blood samples were taken before exercise, immediately after exercise and after 30 minutes of recovery. Data were analyzed by repeated measure ANOVA and Bonferroni test and Pearson's correlations were performed to identify possible relationship among the assessed variables. Statistical significance was set at p