ABSTRACT
Objective: to determine the frequency of restrictive pulmonary dysfunction in type 1 and type 2 diabetic patients and to measure the severity of pulmonary dysfunction
Material and Methods: this study included 255 patients of type I and type II diabetes who had followed up in the out patient departments of Pulmonology and Medicine in Mayo Hospital, Lahore. Forced vital capacity [FVC] and forced expiratory volume in 1 second [FEV1] were measured using standard spirometry
Results: mean age was 47.26+/-19.076 years. 230 [90.2%] were males and 25 [9.8%] were females. 58 [22.7%] were type 1 diabetics and 197 [77.3%] were type 2 diabetics. 37 [14.5%] had restrictive pathology, 6 [2.4%] had obstructive pathology and 212 [83.1%] had normal lung function tests. 35 [13.7%] had mild restrictive dysfunction and 2 [0.8%] had moderate restrictive lung dysfunction
Conclusion: These data support the notion that the lung is a target organ for diabetic injury. Additional research is required to identify pathophysiologic mechanisms and to determine clinical significance
ABSTRACT
Short stature with loss of secondary sex characters can occur due to genetic disorders. One of them is Kallmann's syndrome. The condition has been noted to be present in families. It is associated with anosmia and hypogonadism. We are presenting a case of young boy who was short statured and had anosmia with multiple hormonal deficiencies
Subject(s)
Humans , Male , Hypogonadism , Olfaction DisordersABSTRACT
Chronic rheumatic heart disease is the commonest cause of mitral stenosis. Incidence of rheumatic MS parallels that of acute rheumatic fever. Atrial fibrillation usually develops in the presence of pre-existing ECG evidence of left atrial enlargement and is related to the size of the chamber, the extent of fibrosis of the left atrial myocardium, the duration of the atriomegaly and the age of the patient. The tendency for development of systemic embolization correlates directly with the patient's age and the size of the left atrial appendages and inversely with the cardiac output. Eighty percent of the patients of MS in whom systemic emboli develop are in atrial fibrillation. A descriptive study was designed in the Department of Medicine, K E Medical College / Mayo Hospital and Punjab Institute of Cardiology, Lahore. A total of 129 conservative cases of mitral stenosis were included in this study, based upon convenient patient sampling. A total of 112 patients were followed up properly, the remaining 17 were lost to follow. The results showed left atrial size and MVA have an inverse correlation [p = 0.017]. LAT has a strong association with AF in cases of MS [p = 0.002]. The severity of MS does not influence the frequency of AF [p = 0.24]. It was thus concluded that left atrial size and MVA have an inverse correlation [p = 0.017]. LAT has a strong association with AF in cases of MS [p = 0.002]. The severity of MS does not influence the frequency of AF [p = 0.24]
ABSTRACT
Diabetic ketoacidosis is a known complication of diabetes mellitus. The annual incidence of diabetic ketoacidosis [DKA] among subjects with type 1 diabetes is between 1% and 5% in European and American series respectively. This incidence appears to have remained relatively constant over the last decade in western countries whereas 20-30% of cases occur in newly diagnosed patients. Mortality rate is reported less than 5% in experienced centres whereas internationally overall mortality is 1-10 percent. The objective of this study was to find out mortality rate in patients of diabetic ketoacidosis admitted to east medical ward of Mayo Hospital, Lahore. A descriptive retrospective study was conducted on patients admitted to East medical ward with the diagnosis of DKA. There were 44 patients included in this study. Regarding outcome of patients 84.1% of patients were discharged. The mortality was found to be 15.9% that is much higher as compared to other studies where it was around 5%