Antioxidant red cell protective enzymes in lymphoma patients

Erythrocyte glutathione peroxidase and superoxide dismutase being two important antioxidant protective enzymes that play a decisive role in the integrity and life span of red cells, their activities were estimated in ten untreated lymphoma patients and in ten healthy controls of matching age and sex. Malonyl dialdehyde product of peroxidation of polyunsaturated fatty acids and possible red cell membrane damage - was also estimated in the erythrocytes of both groups. In lymphoma patients, the two antioxidant enzyme were significantly lower, while malonyl dialdehyde was significantly higher than in the control group. The clinical implications of these findings are discussed

Treatment results of hepatocellular carcinoma

Thirty two patients with histologically proven hepatocellular carcinoma were studied. The median age was 55 years. Twenty nine cases were males and three were females. The commonest presentation was upper abdominal pain and abdominal swelling. A common finding was the history of hepatitis, the presence of hepatic fibrosis and the elevation of serum alpha feto protein. Single agent chemotherapy was used in 11 cases. Combination chemotherapy was used in 3 patients. Chemotherapy was followed by segmental resection in two cases. Localized palliative irradiation was used in 4 cases. Fourteen patients were given only symptomatic treatment and had a survival