ABSTRACT
Palisaded, encapsulated neuroma is characterized clinically by a solitary, slowly-growing and dome-shaped papule or nodule, usually accompanied by telangiectasia on the surface, and histopathologically by an encapsulated nodule in the dermis and the palisading arrangement of nuclei. A 57-year-old female patient presented with a 1cm-sized, solitary nodule on the right ala nasi which had been present for about 5 years. The nodule had a tendency to slow growth and it became a polypoid nodule. Telangiectasia was shown on the surface of the lesion. Histopathlogical findings showed a well-defined and encapsulated nodule in the dermis, composed of spindle cells with basophilic and plump nuclei in a palisading fashion. On immunohistochemical staining, the tumor cells of the nodule were positive for S-100 protein, while the capsule of the nodule was negative for S-100 protein. Epithelial membrane antigens were focally positive only on the capsule of the nodule. We report herein a case of palisaded, encapsulated neuroma, one case of which has been reported in Korea.
Subject(s)
Female , Humans , Middle Aged , Basophils , Dermis , Korea , Mucin-1 , Neuroma , S100 Proteins , TelangiectasisABSTRACT
Pseudallescheria (P.) boydii is a true fungus that is ubiquitous in nature, and has a world-wide distribution. It has been isolated from soil, plant debris, polluted water and sewage. Infection may occur via direct inoculation or inhalation, and usually affects the extremities. It is a common cause of mycetoma characterized by tumefaction, draining sinuses and grains. It has polymorphism due to a complicated life cycle which undergoes teleomorph as well as anamorph stages. Cleistothecia, ascocarp and ascospore may be seen during the teleomorph stages, whereas scedosporium and graphium type may be seen during the anamorph stages. We report a case of P. boydii mycetoma occurring in a 69-year old male. He had multiple nodules with a discharging fistula on a dark red plaque at the dorsum of the right forearm. Cultural isolation for definitive diagnosis showed typical P. boydii. The lesion responded well to daily itraconazole.
Subject(s)
Aged , Humans , Male , Edible Grain , Diagnosis , Extremities , Fistula , Forearm , Fungi , Inhalation , Itraconazole , Life Cycle Stages , Mycetoma , Plants , Pseudallescheria , Scedosporium , Sewage , SoilABSTRACT
We report herein a case of Gianotti-Crosti syndrome showing unusual features. A 12-month-old male patient presented with papular skin lesions on his face and papulovesicular skin lesions on the trunk, upper and lower extremities, which were distributed symmetrically. Three days before the skin eruptions, he had been immunized with a measles vaccination. Serologically, antigens of the type B hepatitis virus and antibodies to coxsackie virus B-4, Epstein-Barr virus, and varicella-zoster virus were all negative and antibodies to the measles virus (IgG, IgM) and the type B hepatitis virus were positive. After conservative treatment the skin lesions subsided with exfoliation within 4 weeks. An association with the measles vaccination and the initial papulovesicular skin lesions are considered as peculiar features of this case.
Subject(s)
Humans , Infant , Male , Acrodermatitis , Antibodies , Hepatitis Viruses , Herpesvirus 3, Human , Herpesvirus 4, Human , Lower Extremity , Measles , Measles virus , Skin , VaccinationABSTRACT
We report a case of follicular mucinosis which oecurred in a 28-year old female. She had an adult fist-sized erythemlatous indurated infiltrative plaque with an ill-defined border on the left cheek area. Histopatholcigical findings, including mucin stains, showed characteristic reticular degeneration and cystic spece formation in hair follicles and sebaceous glands with mucinous degeneration and infiltration of abundant eosinophiles. The present case should be differentiated from plaque type eosinophilic pustular folliculitis clinically and histologically.
Subject(s)
Adult , Female , Humans , Cheek , Coloring Agents , Eosinophils , Folliculitis , Hair Follicle , Mucinosis, Follicular , Mucins , Sebaceous GlandsABSTRACT
We report three cases of unusual eosinophilic pustular folliculit is whose initial manifestation is indurated plaque rather than papule and pustule and one case of eosinophilic pustular folliculitis was found in an infant. None of the adult patients in these cases complained of any suhjective syrnptoms other than the skin lesion, but an itching sensation might be present in the case of the infant. In laborat ory test, eos nophilia was observed in only one case and any other abnormal results were not observed. In all cases, histopathologic study revealed numerous eosinophilic infil tration around the follicles exttending to the periappendageal and perivacscular area, that is consistent with the finfings of eosinophilic pustuar folliculitis. All adult patients relatively responded well to dapsone and topical stroid and the infant patient resporided well to topical steroids, But they had a chronic course with remission and exacerhation.