Study of the testis and accessory sex organs in experimental diabetes-1 histological changes

The adverse effect of diabetes induced experimentally by SZ on the testis and accessory sex organs of the male mouse was investigated. Diabetes was assessed by detecting blood glucose level, blood insulin by detecting the blood glucose level, blood insulin level in keeping a regular record of the mean body weight. Animals from both groups were sacrificed after 14, 30 and 60 days from injection. Atrophy of the testis, seminal vesicles and prostate were apparent together with impairment of testicular spermatogenesis and reduction of the number of sperms in the epididymis. Mucosal lining of the sex glands studied revealed a marked atrophy which reflected impaired levels of testosterone as well as insulin