ABSTRACT
Background: Assessment of nuclear morphology is crucial for the diagnosis of non-Hodgkin's lymphoma. The non-Hodgkin’s lymphomas (NHL) constitute a heterogenous group of lymphoid neoplasms that vary in clinical behavior, histology, immunology and genetic profile. The diversity makes it difficult to diagnose accurately and reproducibly under light microscopy. The nuclear features play a major role in categorizing non-Hodgkin's lymphomas. Materials and methods: The present study was conducted for a period of two years in the Department of Oral Pathology, MNR dental College and Hospital, Sangareddy, Telangana, India. We encountered only three cases of Non-Hodgkin Lymphomas and so we have borrowed the some Sridhar Reddy Erugula, P. Sujatha, Ayesha Sameera, B. Suresh Reddy, Jesudass Govada, G. Sudhakar, Kandukuri Mahesh Kumar. Nuclear morphometric study of Non-Hodgkin's Lymphoma (NHL). IAIM, 2016; 3(5): 58-63. Page 59 specimens of NHL from other hospitals in Hyderabad, India. Hematoxylin and Eosin (H and E) stained histological sections were selected and assessed for nuclear area, perimeter and nuclear size of 40 nuclei of tumour cells were measured using the Windows® based image analysis software Results: Total number of cases in our study was 15. The mean nuclear area, perimeter and nuclear size of neoplastic cells were studied. In our study, the mean nuclear area, perimeter and nuclear size of neoplastic cells were significantly high in large cell lymphomas as compared to intermediate cells and small cell lymphoma. P value was significant. Conclusion: Our study supports the assumption that nuclear morphometry offers a more objective and reproducible diagnostic method for subcategorizing lymphoid tumors than is currently possible by conventional histopathological techniques.
ABSTRACT
Despite widespread nutritional deficiencies, investigations of usual diet in rural South Asia remain sparse. The present study characterizes year-round and seasonal dietary patterns of women in the Terai of Nepal by sociodemographic status, using a novel, weekly single-visit and usual food frequency questionnaire that links recall to the agricultural season. The study was conducted across seasons in 2006-2008 among 15,899 women of reproductive age in Sarlahi district. Intakes were tabulated for all foods, overall and by socioeconomic status (SES), and in and out of season, as appropriate. Foods consumed regularly [median (interquartile range) weekly frequency] were rice [13 (7-13)], potatoes [10 (5-13)], legumes [6 (2-9)], and vegetable oil [13 (13-13)]. Animal products were infrequently consumed [1 (0-2) time per week] as were fruits and vegetables, most with a median weekly intake frequency of 0. Higher SES was associated with more frequent consumption of most food-groups, including in-season fruits and vegetables. Diets of women in the Terai of Nepal lack diversity and, likely, nutrient adequacy, which may pose health risks.