ABSTRACT
Objectives: To observe and assess the efficacy of Aloe Vera extract on skin wound healing
Study Design: Analytic and experimental
Place And Duration: Departments of Physiology, Pathology and Postgraduate Research Lab of ISRA University Hyderabad, from June 2011 to December 2011
Methodology: 20 millimeter long cuts were made over the back of 18 rabbits. The rabbits were divided into three groups A,B and C, each comprising 06 numbers, and treated daily for 11 days with Xylo Aid, mixture of Xylo Aid and Alo Vera extract and Aloe Vera extract, and marked blue, black and green respectively. Taking the operation day as zero, 3 rabbits were sacrificed after 24 hours and then alternatively till the llth post-operative day. The entire wound area along with 4-5 mm of the surrounding skin was excised and fixated in 10% formaldehyde, after processing sections were made stained with Hand E and observed under microscope, the fibroblasts were counted to see the quality of wound healing, keeping group A as control the results were tabulated
Results: Visual observation showed that by llth day post wounding the recovery was 75% approximately with Aloe Vera extract application, 50% and 30% was observed with mixture application and Xylo Aid respectively
Conclusion: Aloe Vera application for 11 days on rabbit skin wound showed better healing process in comparison to mixture and Xylo Aid