ABSTRACT
Despite the possibility of curing TB with medical therapy, it has a sizable impact on the lives of afflicted patients. This study aimed to evaluate of treatment effect of anti-tuberculosis drugs on the quality of life on tuberculosis patients admitted in Imam Khomeini hospital in Tehran. The investigation was a before and after study. It was done in 2006-2007 by fill in Persian translated questionnaire of WHOQOL- BREF on 46 pulmonary or extra pulmonary TB infected patients. Paired samples T-test was performed to find out the differences. After 8 weeks of treatment, mean score elevation was significant in physical [15.76 +/- 23.89, p<0.001], psychological [7.84 +/- 17.57, p=0.004], and social [6.83 +/- 19.48, p=0.02] domains. It was not significant in environmental domain [2.15 +/- 8.48, p=0.09]. Mean score elevation at the discharge time in physical, psychological, social and environmental domains were: [5.65 +/- 16.56, p=0.09], [11.69 +/- 19.22, p=0.001], [1.04 +/- 8.60, p=0.41], and [4.37 +/- 17.77, p=0.1], respectively. In our study, after treatment of tuberculosis, patient's physical, psychological and social -not environmental- domains of quality of life were elevated, but at the discharge, there was a significant elevation in physical and psychological domains. These results emphasize the importance of patient's treatment at the first days of admission, with special attention to social and environmental domains