ABSTRACT
Background: several studies have emphasized the importance of cardiovascular disease [CVD] prevention. However, there is a dearth of data on the prevention of cardiovascular disease recurrence. The present study was the 1st in Iran to evaluate factors associated with CVD recurrence
Methods: this prospective cohort study was conducted on 483 subjects [> 30 years old] with a history of CVD who participated in the Tehran Lipid and Glucose Study and were followed up for 12 years [1999-2012]. The relationships between the most important established risk factors for CVD and CVD recurrence were evaluated
Results: totally, 258 [53.4%] men and 225[46.5%] women at a mean age of 59.2 +/- 10.7 years were recruited in the study. Our results showed that over the 12-year follow-up, the incidence of a recurrent event [per 100 person-years] was 48.5. Further, after controlling the possible confounding factors, the following variables had a significant relationship with CVD recurrence: age [HR = 1.02; p value = 0. 001], male sex [HR = 1.4; p value = 0.012], smoking [HR = 1.7; p value = 0.004], and increased fasting blood sugar [HR = 2.1; p value = 0.001]
Conclusion: we found that the established variables in the development of CVD [i.e., age, sex, and smoking] played an important role in the risk of CVD recurrence