A Case of High-Grade B Cell Lymphoma, Not Otherwise Specified Originating From Interior Turbinate / 대한이비인후과학회지

High-grade B cell lymphoma not otherwise specified (HGBL, NOS) is a new diagnostic category of non-Hodgkin lymphoma (NHL) based on World Health Organization statement in 2016. Up to 40% of NHLs are located in the extra-nodal area, commonly involving the gastrointestinal tract, head and neck region, bone and skin. The diagnosis of NHL originating from the inferior turbinate (IT) is rare, and there have been no reported cases yet of HGBL, NOS in IT. In this study, we report on a 43-year-old female who had a nasal polyp in IT and was diagnosed with HGBL, NOS after surgery. Endoscopic polypectomy under general anesthesia was performed. A histopathological report confirmed the resected specimen as HGBL, NOS, with a clear resection margin. Nasal obstruction was improved immediately after surgery and the patient was followed up for 10 months without any recurrence or complications.

A Case of Nasopalatine Duct Cyst with Cholesterol Granuloma in Maxillary Sinus / 대한이비인후과학회지

Nasopalatine duct cysts are the most common non-odontogenic cysts that occur in the maxilla. Cholesterol granulomas, on the other hand, are commonly found in patients with chronic middle ear disease, but rarely occur in the paranasal sinuses. We report a rare case of a 30-year-old woman who was treated for a nasopalatine duct cyst and cholesterol granuloma at the same time. The patient complained of sudden nasolabial pressure and right nasal obstruction from three weeks ago. A 3 cm sized cystic mass, diagnosed as a nasopalatine duct cyst, was observed in the maxilla and haziness of the right maxillary sinus suspected of chronic rhinosinusitis was detected by computerized tomography. Marsupialization of the nasopalatine duct cyst was performed through the endoscopic transnasal approach. Solid mass in the maxillary sinus, diagnosed with cholesterol granuloma by pathology after surgery, was completely removed by endoscopic sinus surgery. The patient was followed up for 18 months without any recurrence or complications.

A Case of Choanal Polyp Originated from the Inferior Turbinate / 대한이비인후과학회지

The choanal polyp, originating from inferior turbinate, is known to be extremely rare. We report a case of a 65-year-old woman who was treated for choanal polyp originating from inferior turbinate. She had felt left nasal obstruction for two weeks. In the endoscopic examination, polypoid tissue covered with the mucopurulent discharge was observed filling the left inferior meatus. An ovoid homogenous enhancing lesion in the left posterior nasal cavity around the inferior turbinate was observed on CT and MRI. Endoscopic mass excision with partial inferior turbinectomy was performed under general anesthesia. The pedicle of the polyp was observed on the posterior side of the inferior turbinate. Complete resection including the mucosa around the pedicle of the choanal polyp was performed. The patient was followed up for seven months without any recurrence or complications.

Angiomyolipoma of the Nasal Cavity Resected with Preoperative Angio-Embolization / 대한이비인후과학회지

Angiomyolipomas (AML) are generally known as benign tumors. The kidney is the most common location of this tumor, and the liver is reported as the second most common site. Occurrence in other tissues is extremely rare. For instance, some cases of AML originating from the nasal cavity have been previously reported. We describe an AML case arising from the nasal cavity of a 56-year-old man. The patient had been complaining of nasal obstruction and foreign body sensation in the nasopharynx and was initially treated with preoperative angio-embolization. AML was then totally removed by endoscopic surgery without complications. He has been asymptomatic and has had no evidence of recurrence for 2 months after surgery.

A Case of Inflammatory Pseudotumor in Temporal Bone Treated with Methotraxate / 대한이비인후과학회지

Inflammatory pseudotumor is a pathologically benign condition, but it demonstrates a wide range of clinical features ranging from silent small sized tumors to aggressive features mimicking malignancy. Pseudotumors most commonly occur in the orbital area, and the involvement of the middle ear cavity is extremely rare. Several modalities are known for the treatment of pseudotumors, including complete surgical excision, oral steroid therapy, and radiation therapy. We describe a 35-year-old woman with inflammatory pseudotumor involving the middle ear cavity. The patient was treated with canal wall up tympanomastoidectomy and additional treatments with steroid and radiation therapy. However, she showed side effects to high dose steroid treatment and no response to radiation therapy. Therefore, we decided to use methotrexate with low dose steroid. After treatment, symptoms were completely resolved and there was no evidence of recurrence 1 year after maintaining immunosuppressant treatment.

Two Cases of Malleostapedotomy in Congenital Oval Window Atresia

Congenital anomaly of the oval window with an abnormal facial nerve course is an uncommon embryological defect, which is related to the underdevelopment of second branchial arch derivatives. Some treatments for improving hearing levels are available; these include hearing aids, vestibulotomy, neo-oval window formation, and stapes surgeries, including incudostapedotomy and malleostapedotomy. However, surgery for congenital anomalies of the oval window has rarely been described, usually in very small series of patients. We describe two cases of congenital anomalies of the oval window with aberrant facial nerve courses. One was a 40-year-old male diagnosed with unilateral congenital oval window atresia; the other was a 10-year-old male diagnosed with bilateral congenital oval window atresia. We also describe the clinical manifestations and treatment outcomes of malleostapedotomy for congenital anomalies of the oval window with aberrant facial nerve courses.