The Usefulness of Non-contact Erection Observation for Evaluation Sexual Function in Male Rat / 대한비뇨기과학회지

PURPOSE: Evaluation of sexual function is an important step for animal studies about sexual function. Male rats could display penile erection in the presence of an inaccessible estrous female. We examined the usefulness of observing non-contact erection (NCE) for the evaluation of sexual function in male rats. MATERIALS AND METHODS: Forty five Long-Evans male rats (8 weeks old) were used in this study. Tests for NCE were conducted in a glass chamber divided in half by 2 wire-mesh screens that prevented direct contact, but the rats freely passed other forms of stimulation. If at least 1 NCE could be observed during 45 minutes, we considered this as a positive response. In case of two or three positive responses in three NCE tests, that was considered as NCE (+). After NCE, copulation observations were noted to evaluate sexual function. If at least two ejaculations could be observed during 45 minutes, we considered that a positive response. In case of two or three positive responses in three copulation observations, that was considered as normal sexual function. RESULTS: Twenty one of 45 male rats (47%) were NCE (+) and 34 of 45 male rats (76%) had normal sexual function. In 21 NCE (+) rats, 20 rats had normal sexual function: only one was impotent. The positive predictive value of the NCE observation for the evaluation of sexual function was 95%. In 11 impotent rats, 10 rats were NCE (-). The specificity of the NCE observation was 91%. CONCLUSIONS: These results indicated that NCE observation could be a useful method for evaluating the sexual function of male rat.

The Incidental Polyorchidism and Treatment: Report of 2 cases / 대한비뇨기과학회지

Herein, polyorchidism possessing of more than the usual number of testicles, which was found in two patients, is reported. Both patients had three testes, and one presented with painful swelling of the right scrotum caused by torsion of the testis and the other revealed a non-palpable testis in the right hemiscrotum. Both patients were managed surgically with orchiopexy and an orchiectomy, respectively, followed by the insertion of an artificial testis.

Usefulness of Urodynamic Study in Diabetic Cystopathy / 대한비뇨기과학회지

Sixty diabetic cystopathy patients (symptomatic DCP, 4.9%) among 1236 patients of diabetes mellitus (DM) from May, 1995 to June, 1996 were analyzed to ascertain the usefulness of urodynamic study in the diagnosis of DCP. The mean age was 58 (24--80) years and mean duration of DM was 9 (1~30) years. 36 (60%) patients had diabetic neuropathy, 31 (52%) had diabetic retinopathy and 4 (7%) had diabetic nephropathy. DM was managed by insulin pump (DIABECARETM, 52%) and subcutaneous insulin injection (42%). In residual urine and voiding diaries, residual urine volume more than 40ml was 83%, voiding interval less than 2 or more than 5 hours was 67% and voiding amount less than 200ml or more than 400ml was 48%. According to urodynamic findings, patients were classified as detrusor areflexia (63%), impaired detrusor contractility (18%), detrusor instability (15%) and normal detrusor contraction (3%). There were no significant differences of age, semm-HbA1C, treatment method and duration of diabetes mellitus among above groups. Mean duration of DM in irritative symptom group (32%), combined symptom group (23%) and obstructive symptom group (45%) were 2 years, 8 years and 15 years respectively (p<0.001). The shape of the cystometrographic curve was not influenced by the rate of bladder filling (40ml/min versus 100ml/min). In conclusion, because DCP is marked by insidious onset and progression with minimal symptoms, DCP can be early diagnosed using urodynamic study especially in patients with voiding symptoms and 1ong.DM duration.

Significance of urine dipstick in the evaluation of hematuria in patient with renal trauma / 대한비뇨기과학회지

Hematuria has been the most reliable sign of injury to the urinary system. Thus. the rapid and accurate detection of hematuria in the emergency room is essential. In 149 patients with renal trauma in whom radiographic studies defined the severity of injury, we compared the degree of microscopic hematuria determined by dipstick and microscopic urinalysis. Falge positive dipstick occurred in 5(3.6%) patients and false negative dipstick in 4(3.3% ) patients. The dipstick method had greater than 96.4 percent sensitivity and specificity for detection of microscopic hematuria. The correlation between the 2 methods was low (Person`s coefficient 0.4114). However. 85.5 percent or the urine sample with more than 20 red blood cells per high power field corresponded to a dipstick results of 3+ (Regression Y = 0.0129x + 2.93, F = 28.12. p < 0.005). Although microscopic hematuria may be quantified more accurately by microscopic analysis, the urine dipstick is a rapid and reliable screening test with high degree of sensitivity and specificity for the microscopic hematuria in patients with renal trauma.

Validity of 99m Tc-dimercaptosuccinic acid scan for detection of renal scarring / 대한비뇨기과학회지

The early radiological investigations of urinary tract infection are justified nowadays in order to identify those whose kidneys are already damaged, those who may be at risk of progressive damage, and those in whom a treatment program is indicated. 42 children who performed 99mTc-dimercaptosuccinic acid scan in the diagnostic step of recurrent urinary tract infection for recent 3 years at Severance Hospital were evaluated to access the validity of 99 m Tc-dimercaptosuccinic acid scan in detection of pyelonephritic scarring. The results were as follows: 1. Renal cortical defects were detected in 34 kidneys among 84 kidneys(40.5%) by DMSA scan, intravenous pyelography and ultrasonography 2. DMSA scan was significantly more valuable in detecing renal defect than intravenous pyelography (P<0.05). 3. The presence of reflux on voiding cystourethrography showed a significant correlation with renal cortical defects seen on DMSA scan (P<0.05). 4. The sensitivity of the DMSA scan in screening for all grades of reflux was estimated 0.9 and DMSA scan never missed renal defects in high grade (III-V/V) reflux. So we conclude that 99 m Tc-DMSA scan is more useful than other upper urinary tract imaging technique in detecting renal defects and consideration should be given to their use as first line of study for screening of renal defect in urinary tract infection and vesicoureteral reflux.

A case of apocrine sweat gland carcinoma in the scrotum / 대한비뇨기과학회지

Apocrine sweat gland carcinoma is a very unusual malignant skin adnexal tumor and mostly occurs in areas where apocrine elands are abundant namely. axilla. upper arm. scalp. eyelid. vulva and external auditory meatus. The scrotal location is not yet reported. We report a case of apocrine sweat gland carcinoma of scrotum in a man aged 85, which was managed by local excision. The histologic finding is that of poorly differentiated adenocarcinoma. Evidence of decapitation secretion typical or apocrine glands. is present in some areas.

Primary Adenocarcinoma of the Bladder Treated by Pelvic Exenteration : Report of A Case / 대한비뇨기과학회지

Adenocarcinoma of the bladder is a rare tumor. It's incidence figures in the ranges of 0.5 to 2.0 percent of all epithelial bladder neoplasms. Adenocarcinoma of the bladder occurs more frequently in areas which schistosomiasis is endemic and is the most common malignant tumor arising in the exstrophic bladder or urachus. Primary adenocarcinoma of the bladder must be carefully differentiated from the adenocarcinomas that originate within the urachus, prostate, seminal vesicle, breast, gastrointestinal tract or other organs. This report describes a 43 years old male who was diagnosed as an infiltrative adenocarcinoma of the bladder by the preoperative evaluation and transurethral resection of bladder and was confirmed by the pathologic examination following pelvic exenteration as the primary adenocarcinoma or the bladder extended to the prostate and rectum and was followed by chemotherapy without evidence of metastasis.

Primary Hyperparathyroidism in Recurrent Urolithiasis: 1 Case / 대한비뇨기과학회지

Primary hyperparathyroidism is not a rare disease, but only several cases have been reported in Korean literature. Recently, we experienced one case of primary hyperparathyroidism with hypercalcemia, hypercalcemia, recurrent stone attacks and pathologic fracture. The patient underwent parathyroidectomy, which revealed parathyroid adenoma. The serum calcium, urinary calcium and parathyroid hormone levels were normalized postoperatively.