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2.
Journal of the Korean Academy of Rehabilitation Medicine ; : 714-719, 2001.
Article in Korean | WPRIM | ID: wpr-724061

ABSTRACT

Dominantly inherited spinocerebellar ataxias (SCAs) are a group of the heterogenous neurodegenerative diseases that are characterized by chronic progressive cerebellar ataxia associated with various combinations of other neurological signs. Clinical classification is difficult because of the phenotypic overlap. With the evolution of molecular genetics, the loci and mutations for many of the ataxias have been identified, allowing more definitive molecular classification. We experienced 42 years-old man who presented with progressive both lower leg weakness, dysarthria, ataxia, ophthalmoplegia, and nystagmus. The family history was remarkably suspicious. We could not observe the upper extremity weakness, definite evidences of peripheral neuropathy and myopathy in electrodiagnosis. No abnormal findings in blood chemistry and brain MRI. We performed polymerase chain reaction (PCR) and polyacrylamide gel electrophoresis (PAGE) analysis, found that his gene contained expanded CAG repeats (CAG repeat number was 72). Although no effective treatment exists for most the ataxic syndromes, the accurate diagnosis and the genetic counseling are often important to the patient's family for prognostication.


Subject(s)
Adult , Humans , Ataxia , Brain , Cerebellar Ataxia , Chemistry , Classification , Diagnosis , Dysarthria , Electrodiagnosis , Electrophoresis, Polyacrylamide Gel , Genetic Counseling , Leg , Machado-Joseph Disease , Magnetic Resonance Imaging , Molecular Biology , Muscular Diseases , Neurodegenerative Diseases , Ophthalmoplegia , Peripheral Nervous System Diseases , Polymerase Chain Reaction , Spinocerebellar Ataxias , Upper Extremity
3.
Journal of the Korean Academy of Rehabilitation Medicine ; : 538-543, 1999.
Article in Korean | WPRIM | ID: wpr-723615

ABSTRACT

OBJECTIVE: To evaluate the change of abnormal spontaneous activities according to the clinical and radiologic findings, and to the time course after onset in hemiplegic upper limb. METHOD: We scored abnormal spontaneous activities of hemiplegic upper limb muscles (infraspinatus, deltoid, extensor carpi radialis, abductor pollicis brevis, abductor digiti minimi) in 100 hemiplegic patients without peripheral neuropathy. The abnormal spontaneous activities were evaluated according to their radiologic findings and to Brunnstrom stage and the presence of reflex sympathetic dystrophy (RSD), and the time course after the onset (A cross-sectional study). In addition we repeatedly examined 40 hemiplegic patients until 12 weeks after the onset to define the pattern of change (A prospective study). RESULTS: There was no significant difference in the score of abnormal spontaneous activities according to the radiologic findings. The score of abnormal spontaneous activities decreased while Brunnstrom stage progressed. In both the cross-sectional and prospective studies, we found that the abnormal spontaneous activities decreased according to the time course after the onset in the limb without RSD, but sustained in the limb with RSD. CONCLUSION: Abnormal spontaneous activities decreased according to the progression of Brunnstrom stages. The hemiplegic patients with RSD showed more profuse and sustained abnormal spontaneous activities at needle EMG study of hemiplegic upper limb than the patients without RSD.


Subject(s)
Humans , Extremities , Muscles , Needles , Peripheral Nervous System Diseases , Prospective Studies , Reflex Sympathetic Dystrophy , Upper Extremity
4.
Journal of the Korean Academy of Rehabilitation Medicine ; : 866-870, 1998.
Article in Korean | WPRIM | ID: wpr-724126

ABSTRACT

OBJECTIVE: To assess the abnormal spontaneous activities in needle electromyography (EMG) according to the type of herniated lumbar disc and anteroposterior the diameter of dural sac in magnetic resonance imaging (MRI). METHOD: We performed the MRI on 120 patients with low back pain (LBP) and measured the midline anteroposterior diameter of dural sac in a MRI axial view. Fifty patients with a disc protrusion or extrusion in MRI were reviewed for the clinical findings on physical examination and assessed for the abnormal spontaneous activities (ASA) in needle EMG. RESULTS: Seventy cases with a normal finding in MRI did not have differences in a dural sac diameter regardless their age or sex. Fifty cases with a protrusion or extrusion in MRI showed that the dural sac size decreased more in an extrusion than in a protrusion, and more in a paracentral type than in a central type. The incidence of ASA in a needle EMG increased more in an extrusion than in a protrusion, and more in a paracentral type than in a central type. The incidence also increased according to the decrement of a dural sac diameter. The incidence of ASA were 100% in a group with both motor and sensory signs, 94% in a group with a motor sign, 86% in a group with a sensory sign, 26% in a group without motor or sensory sign. CONCLUSION: We concluded that the abnormalities in needle EMG must be correlated with the direction of herniated lumbar disc and anteroposterior diameter of the dural sac in MRI as well as clinical findings.


Subject(s)
Humans , Electromyography , Incidence , Low Back Pain , Magnetic Resonance Imaging , Needles , Physical Examination
5.
Journal of the Korean Academy of Rehabilitation Medicine ; : 950-954, 1998.
Article in Korean | WPRIM | ID: wpr-724114

ABSTRACT

OBJECTIVE: To evaluate the effects of stellate ganglion block(SGB) in adhesive capsulitis of the shoulder which was not treated with other procedures and therapeutic exercise. METHOD: Fifty patients with adhesive capsulitis of the shoulder were assessed by the shoulder range of motion(ROM) and visual analogue scale before and in 30 minutes after the SGB without other procedures and therapeutic exercise. RESULTS: In 30 minute after the SGB, the shoulder ROM increased 11degrees in flexion, 14degrees in abduction, 8degrees in internal rotation, and 6degrees in external rotation and visual analogue scale decreased (P<0.05). The changes of shoulder ROM after the SGB were not significantly related to duration of the adhesive capsulitis of shoulder, except in flexion. CONCLUSION: The stellate ganglion block can be another effective method for the patients with adhesive capsulitis of the shoulder.


Subject(s)
Humans , Adhesives , Bursitis , Shoulder , Stellate Ganglion
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