Phenomenology on the Hemodialysis Experience of Patients with End-Stage Renal Disease / 재활간호학회지

PURPOSE: This study aimed to explain what are the experiences of patients with renal disease who are just begun hemodialysis in the end-stage. METHODS: The data were collected from February to December in 2017 through individual in-depth interviews using open-ended questions. For data analysis, a phenomenological method suggested by Colaizzi was applied. A total of 8 hemodialysis patients with end-stage renal disease (ESRD) participated in this study. RESULTS: According to the analysis, five theme clusters emerged: ‘I go into darkness’, ‘Being disappearing from others’, ‘Baby bird living with love’, ‘Dawn in darkness’ and ‘A life longing for the absolute’. CONCLUSION: Patients undergoing hemodialysis experienced fear and anxiety at the beginning of hemodialysis. Therefore, counseling and social supports were needed for patients with ESRD in their early stage of hemodialysis. In addition, a multidisciplinary education program should be implemented in the future research. It may help to overcome for the patients who are experiencing complicated health problems in their early stage of hemodialysis treatment.

Retention Effects of Dietary Education Program on Diet Knowledge, Diet Self-Care Compliance, Physiologic Indices for Hemodialysis Patients

PURPOSE: The purpose of this study was to identify the retention effects of an individualized dietary education program for hemodialysis patients on diet knowledge, diet self-care compliance, and physiological indices, thus to find the most effective time period for re-education. Method: This study utilized one-group repeated pretest-posttest design. The participants were 52 hemodialysis patients in C hospital, Gyeonggi-Do. Data were collected at 4 and 12 weeks after the education from January through April 2016. RESULTS: There was significant increases in diet knowledge even 12 weeks after the education (p=.007). Diet self-care compliance showed a significant increase at 4 weeks (p=.001), but a decrease at 12 weeks after the education. The level of blood natrium was significantly decreased between 4 and 12 weeks after the education (p=.006). The weight was significantly decreased at 12 weeks after the education. CONCLUSION: It has been identified that re-education for hemodialysis patients should be implemented between 4 and 12 weeks after education in order to maintain patients' diet self-care compliance, an ultimate aim of diet education. By helping them with their self-care compliance, the patients would maintain their physical and psychological function optimally, thus contributing to a better quality of life among hemodialysis patients.

Jeju seaweeds suppress lipopolysaccharide-stimulated proinflammatory response in RAW 264.7 murine macrophages

<p><b>OBJECTIVE</b>To investigate the anti-inflammatory effects of Jeju seaweeds on macrophage RAW 264.7 cells under lipopolysaccharide (LPS) stimulation.</p><p><b>METHODS</b>Ethyl acetate fractions were prepared from five different types of Jeju seaweeds, Dictyopteris divaricata (D. divaricata), Dictyopteris prolifera (D. prolifera), Prionitis cornea (P. cornea), Grateloupia lanceolata (G. lanceolata), and Grateloupia filicina (G. filicina). They were screened for inhibitory effects on proinflammatory mediators and cytokines such as nitric oxide (NO), prostaglandin E2, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6).</p><p><b>RESULTS</b>Our results revealed that D. divaricata, D. prolifera, P. cornea, G. lanceolata, and G. filicina potently inhibited LPS-stimulated NO production (IC50 values were 18.0, 38.36, 38.43, 32.81 and 37.14 µg/mL, respectively). Consistent with these findings, D. divaricata, D. prolifera, P. cornea, and G. filicina also reduced the LPS-induced and prostaglandin E2 production in a concentration-dependent manner. Expectedly, they suppressed the expression of inducible NO synthase and cyclooxygenase-2 at the protein level in a dose-dependent manner in the RAW 264.7 cells, as determined by western blotting. In addition, the levels of TNF-α and IL-6, released into the medium, were also reduced by D. divaricata, D. prolifera, P. cornea, G. lanceolata, and G. filicina in a dose-dependent manner (IC50 values for TNF-α were 16.11, 28.21, 84.27, 45.52 and 74.75 µg/mL, respectively; IC50 values for IL-6 were 37.35, 80.08, 103.28, 62.53 and 84.28 µg/mL, respectively). The total phlorotannin content was measured by the Folin-Ciocalteu method and expressed as phloroglucinol equivalents. The content was 92.0 µg/mg for D. divaricata, 151.8 µg/mg for D. prolifera, 57.2 µg/mg for P. cornea, 53.0 µg/mg for G. lanceolata, and 40.2 µg/mg for G. filicina.</p><p><b>CONCLUSIONS</b>Thus, these findings suggest that Jeju seaweed extracts have potential therapeutic applications for inflammatory responses.</p>

Gender Differences in Oral Health Literacy related Factors among Elderly People

PURPOSE: This study is to measure oral health literacy levels and to identify oral health literacy related factors in elders. METHODS: The research design for this study was a descriptive survey design using convenience samples. Data collection was done by using a self-report questionnaire with 321 elders from three welfare centers for the aged and two senior centers located in three cities. Data were analyzed by using percentage, mean, standard deviation, t-test, ANOVA, Scheffe, Pearson's Correlation Analysis and hierarchical multiple regression with the SPSS Win 18.0 Program. RESULTS: The oral health literacy scores of male elders were higher than those of female elders (t=9.73, p=.002). In hierarchical multiple regression analysis, education levels, smoking and oral health statuses were significant predictors and accounted for 29.8% of the male elders' oral health literacy. For female elders, education levels, health statuses and oral health statuses were significant predictors and accounted for 47.7%. CONCLUSION: These results suggest that interventions for improving oral health literacy are necessary to enhance elders' ability of self-care management. Also, these results could be used in developing oral health literacy programs.

Jeju seaweeds suppress lipopolysaccharide-stimulated proinflammatory response in RAW 264.7 murine macrophages

Objective: To investigate the anti-inflammatory effects of Jeju seaweeds on macrophage RAW 264.7 cells under lipopolysaccharide (LPS) stimulation. Methods: Ethyl acetate fractions were prepared from five different types of Jeju seaweeds, Dictyopteris divaricata (D. divaricata), Dictyopteris prolifera (D. prolifera), Prionitis cornea (P. cornea), Grateloupia lanceolata (G. lanceolata), and Grateloupia filicina (G. filicina). They were screened for inhibitory effects on proinflammatory mediators and cytokines such as nitric oxide (NO), prostaglandin E

Changes in Smokers' Perception about smoking before and after Participation in a Hospitalized Smoking Cessation Program / 간호학회지

PURPOSE: This study was done to analyze the changes in smokers' subjectivity about smoking before and after participation in a 5-day hospitalized smoking cessation program. Design: Q-methodology, which provides a scientific method on subjectivity, was applied. Findings: Nine types of subjectivity changes about smoking were identified; Type I, Nicotine craving --> Confident of self control for smoking; Type II, Nicotine craving --> Cognition of the link between habituation and smoking, Type III, Nicotine craving --> Nicotine craving, Type IV, smoking as a social behavior --> Cognition of the link between habituation and smoking, Type V, smoking as a social behavior --> Motive to turn away from being addicted to smoking to being healthy, Type VI, Habitual smoking --> Confident of self control for smoking, Type VII, Habitual smoking --> Cognition of the link between habituation and smoking, Type VIII, Habitual smoking --> Motive to turn away from being addicted to smoking to being healthy and Type IX, Denial of the negative effects of smoking --> Confident of self control for smoking CONCLUSION: The types of changes in smokers' subjectivity before and after the smoking cessation program in this study suggest a better tailored intervention for individual smokers. The types of changes on smokers' subjectivity provide insight about which factors of the interventions for smoking cessation are especially valued for a particular group of smokers.

The Types of Smoking Cessation Among Adult Smokers: Q Methodological Approach / 성인간호학회지

PURPOSE: The purpose of this study was to analyze the subjectivity of smoking cessation methods of smokers. METHOD: The Q. methodology which provides a method of analyzing the individual's subjectivity was used. The 34 subjects classified 38 selected Q-statements into a 9 point scale to make a normal distribution. The collected data was analyzed using a QUANL PC program. RESULTS: Three types of smoking cessation among smokers were identified. Type I, Family Centered; Type II, Suppressing Temptation; Type III, Self Overcoming. CONCLUSION: This study results revealed that different approaches of support programs are needed to address the three types of smoking cessation and their characteristics

The Types of Smoking Cessation Among Adult Smokers: Q Methodological Approach / 성인간호학회지

PURPOSE: The purpose of this study was to analyze the subjectivity of smoking cessation methods of smokers. METHOD: The Q. methodology which provides a method of analyzing the individual's subjectivity was used. The 34 subjects classified 38 selected Q-statements into a 9 point scale to make a normal distribution. The collected data was analyzed using a QUANL PC program. RESULTS: Three types of smoking cessation among smokers were identified. Type I, Family Centered; Type II, Suppressing Temptation; Type III, Self Overcoming. CONCLUSION: This study results revealed that different approaches of support programs are needed to address the three types of smoking cessation and their characteristics

Types of Smoking Among Adult Smokers / 기본간호학회지

PURPOSE: This study was done to analyze subjectivity of smoking among adult smokers. METHOD: Q-methodology, which provides a scientific method on subjectivity, was used. RESULT: Five types of smoking among adult smoker were identified Type I, Concerning Significant Others; Type II, Pursuing Psychological Comfort; Type III, Habitual Craving; Type IV, Pursuing Social Relations and Type V, Maintaining Self Control. Stage of change and methods of stress relieving were revealed to be factors influencing the smoking modes among the adult smokers. CONCLUSION: The five types of smoking and factors influencing them as revealed in this study provide a better understanding of smokers. Smoking styles and subjective values about smoking provide insight for nursing interventions for smoking.

MRI Findings of Intracranial IVleningioma: Significance of Gd-DTPA Enhancernent

PURPOSE: To assess the usefulness of Gd-DTPA MRI in the evaluation of the characteristics of intracranial meningiomas and in the correlation with their histopathologic pattern. MATERIALS AND METHODS: We retrospectively analyzed the Gd-DTPA MRI findings in 22 cases of histologicalty-proven intracranial meningiomas. The images were assessed for signal intensity, internal texture, peritumoral edema, and enhancement characteristics. Computed tomograms were obtained in 18 cases and compared with MRI findings. RESULTS: Tl-weighted images were not particularly useful for discriminating pathologic subtype, but signal intensity on T2-weighted images were relatively well correlated with histopathologic findings. A heterogeneous texture produced by tumor vascularity, calcification, cystic foci, hemorrhagic necrosis, or psammoma body was relatively well shown on Gd-DTPA Tl-weighted image compared with that on T1- or T2-weighted image. Gd-DTPA Tl-weighted images revealed a dural tail sign in 19 cases(83%). Angioblastic type was slightly hypointense on Tl-weighted image and markedly hyperintense on T2-weighted image. Psammomatous type and firboblastic type were isointense on both T1- and T2-weighted image. Fibroblastic type was more densely enhanced than the other. The transitional, atypical, and papillary types showed tendency of heterogeneous enhancement. CONCLUSION: Gd-DTPA MRI was a useful imaging modality in evaluation of the characteristics of meningiomas and correlated well with the pathologic patterns.

The Diagnostic Value of MRI for the Differentiation of Benign and Malignant Soft Tissue Masses

PURPOSE: To evaluate the diagnostic value of magnetic resonance(MR) imaging in the differentiation of benign and malignant soft tissue masses. MATERIALS AND METHODS: MR examination of 47 patients with pathologically proven soft tissue masses were reviewed. This series included 19 malignant and 28 benign masses of upper and lower extremities, body, and neck. Lesions were evaluated for their margin, signal intensity and homogeneity, pattern and degree of enhancement, involvement of the adjacent tissue, and degree of surrounding edema. RESULTS: Sixteen of benign lesions(57.1%) had well-defined and smooth margin. The tumor margin was irregular in nine lesions(47.4%), however, smooth margin was noted in five cases(26.3%) of malignant lesions. On T2-weighted images, signal inhomogeneity was noted in 84% of malignant lesions and 32% of benign lesions. On Gd-DTPA enhancement study, all malignant lesions(n=18) showed enhancement and 89% showed heterogeneously enhancing pattern. Neurovascular involvement was observed more often in malignancy(n=7) compared to benign lesion(n=1). Direct invasion of the adjacent bone was noted only in malignant lesions(n=3). Surrounding edema was revealed in two benign and 11 malignant lesions. CONCLUSION: MR imaging appears useful for differentiating malignant and benign lesions by identifying tumor margin, signal homogeneity of tumor, pattern and degree of enhancement, involvement of adjacent tissue, and surrounding edema. The nature of the lesion can be determined in the majority of cases although no unique criterion to differentiate benignancy and malignancy is identified.

Head and Neck Tumors and Neck Node Metastasis: Comparison of Ga-67 Scan and CT Findings

PURPOSE: To assess relative diagnostic value of Ga-67 planar, Ga-67 SPECT, and CT images for detection of head and neck tumors and cervical lymph node metastasis. MATERIALS AND METHODS: Thirty eight patients of pathologically proven head and neck tumors including squamous cell carcinomas(n=32), malignant lymphomas(n=3), undifferentiated carcinomas(n=2), adenocarcinomas(n=l) were enrolled in this study. Ga-67 planar and SPECT images were obtained with intravenous injection of 5mCi of Ga-67 citrate. On the basis of 30 and 20 mm in the greatest diameter of cervical lymph nodes, we compared lesion detectability of Ga-67 planar, SPECT, and CT. RESULTS: Thirty eight cases of head and neck tumors were detected in 29 cases(76.3%) with Ga-67 planar image, 37 cases(97.3%) with Ga-67 SPECT, and 32 cases(84.2%) with CT. 25 of 32 squamous cell carcinomas were positive with Ga-67 planar image and all of 32 cases with Ga-67 SPECT. Both of two undifferentiated carcinomas were positive with Ga-67 planar and SPECT images. Two of three malignant lymphomas were positive with Ga-67 planar image and all of three with Ga-67 SPECT. Eight of nine tumors were negative with Ga-67 planar image and those were less than 30ram. One case of adenocarcinoma was negative with Ga-67 planar and SPECT images. Seven of nine lymph nodes greater than 30mm were positive with Ga-67 planar image and all of nine with Ga-67 SPECT. On the basis of 20mm in greatest diameter, 16 of 21 lymph nodes greater than 20 mm were positive with Ga-67 planar and SPECT images. CONCLUSION: CT providing better resolution than Ga-67 scan permitted analysis of size and location of metastatic cervical nodes, however primary tumors of oral cavity, vocal cord, and nasopharynx were often not detected on CT when metallic and motion artifacts were present, where Ga-67 SPECT was useful. Ga-67 SPECT enabled better anatomical localization than Ga-67 planar image and was useful in detection of lymph nodes greater than 30 mm.