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Arq. neuropsiquiatr ; 61(2A): 226-233, Jun. 2003. ilus, tab
Article in English | LILACS | ID: lil-339491

ABSTRACT

We carried out this work with the purpose of studying the effects of protein and vitamin B deficiency on the morphologic and quantitative aspects of the myenteric plexus of the descending colon of adult Rattus norvegicus. Twenty-eight rats were divided in two groups, one of them receiving chow with 22 percent protein level (control) and the other fed with chow having 8 percent protein level without vitamin B supplementation, during 120 days. Whole-mounts of the descending colon were prepared and stained with Giemsa, NADH-diaphorase and NADPH-diaphorase. The undernourished rats had a body weight 11.84 percent less than the control group. Relative to the controls, the experimental group had a colonic area 48 percent smaller, 51.9 percent less Giemsa-stained neurons, 28.3 percent less NADH-diaphorase positive neurons and 24.2 percent less NADPH-diaphorase positive neurons


Subject(s)
Animals , Male , Rats , Colon , Myenteric Plexus , Neurons , Protein Deficiency , Vitamin B 12 Deficiency , Body Weight , Cell Count , Colon , Dihydrolipoamide Dehydrogenase/metabolism , Myenteric Plexus , NADPH Dehydrogenase , Neurons , Rats, Wistar
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