ABSTRACT
Objective:To compare the serum prolactin level in hyperthyroid and normal control females. Hyperthyroidism is a mutual disease. Even though a direct relation has been demonstrated amid hypothyroidism and increased prolactin levels, this association has not been established for hyperthyroidism
Materials and Methods: Cross sectional study was carried out on cases and control groups. To select the cases, all women referred to the laboratories of Saudi National Hospital with a thyroid-stimulating hormone [TSH] level 0.5 mIU/L and met the inclusion criteria were entered in the study. A total of 62 women aged 16 to 49 years were enrolled. The case group included 24 hyperthyroid women, and the control group included 38 women with normal thyroid function matched by age
Results: The mean [SD] serum level of prolactin was 16.4 [0.96] ng/mL [95% confidence interval [CI], 15.39 ng/mL to 15.69 ng/mL] in the controls and 23.02 [1.47] ng/mL [95% CI, 22.7 ng/mL to 23.4 ng/mL] in the case subjects. Hyperprolactinemia was more common in the hyperthyroid group [16.4 [0.96] ng/mL versus 23.02 [1.47] ng/mL; P<.001]. The prolactin level decreased with age. Hyperthyroidism and estradiol increased the prolactin level. After adjusting for age and estradiol, hyperthyroidism increased the serum prolactin level [P<.001]
Conclusion: The outcomes of the present study showed that hyperprolactinemia is more frequent in hyperthyroid females. Serum prolactin level can be increased in hyperthyroidism
ABSTRACT
Menstrual disorders and abnormal uterine bleeding are common worries of young women. Complaints comprise menses that are: too painful [dysmenorrhea], prolonged and heavy [menorrhagia, or excessive uterine bleeding], or absent or arise irregularly [amenorrhea or oligoamenorrhea]. In providing optimal reproductive care, the medical provider should be capable of distinguishing between normal developmental patterns or symptoms necessitating education and reassurance from pathologic conditions needing early evaluation and management. This article discusses the normal menstrual patterns seen in adolescent females and provides treatment and management approach to primary and secondary dysmenorrhea