ABSTRACT
Purpose@#Follow-up examinations in kidney donors is an essential yet necessary process in organ transplantation. In this study, we aimed to evaluate kidney function using biomarkers and biomarker based eGFR in kidney donors within 5 years of organ transplantation.@*Materials and method@#91 donors enrolled in our study. We measured body weight and blood and urine samples for laboratory tests. eGFR was calculated using 6 estimations.@*Result@#The mean serum creatinine in participants was 0.81±0.22 mg/dL, cystatin C was 1.11±0.19 mg/dL, urea was 31.44±8.02 mg/L. Systolic hypertension in subjects was 130.0±16.5 mmHg while diastolic hypertension was 78.4±10.8 mmHg. In all donors, 15.9% (n=14) had hematuria, 23.6% (n=21) had proteinuria, 24.7% (n=19) had albuminuria. Body weight, creatinine, cystatin C and urea measurements had gradually increased over the years. The average eGFR was 72.9±17.9 to 112.8±34.0 ml/min/1.73m<sup>2</sup> showing 0.15%-35.22% before donation. Follow – up rate was 28.3-59.2% of total donors.Having health insurance and living far from Ulaanbaatar city influenced follow – up rate. Donor registration data should be updated regularly. @*Conclusion@#</br> 1. Serum creatinine, cystatin C, urea was increasing in living kidney donors. Hypertension and microalbuminuria was greater than other donor study results. </br> 2. eGFR decreased 0.15-35.22% in donor. CKD EPI combined equation was best for donor. </br> 3. Health insurance and living far from Ulaanbaatar city were the influencing follow – up rate. Registration data is missing in 25.5%-82.4% of total donors suggesting enhancement in data collection.
ABSTRACT
INTRODUCTION:Breast cancer is one of the most common cancers in the world. According to the WHO report, over 14.1million new cases were registered every year. 6% of all cancers of Mongolian women were indicated asa breast cancer. This is the 2.5% of cancer cases of whole Mongolian population.GOAL:Identify observed 5 year survival rate and mean of survived time of patients with breast cancers inMongolian population, and some risk factors of survival.MATERIALS AND METHODS:The study design was retrospective and a total of 195 patients were selected which are registered bybreast cancer in National Cancer Registry of Mongolia, 2007-2008 years. Average of survival timecalculated by median and mean, observed 1, 3, 5 year survival rate calculated by percent. Data analyseswere performed using SPSS 19.0 software.RESULT:Totally 195 people involved in research, 5 year after diagnosed 59 (30.3%) people died from cancer, 136(69.7%) people was alive.Breast cancer patients observed 1, 3, 5 year survival rate was correlated to age group, level of education,stage of diagnosis and get involved cancer treatment.Breast (Wald (3) =26.30, P<0.0001) cancer patients survival was correlated to stage of diagnosis and getinvolved cancer treatment.CONCLUSION:1. Mean of survived time of patients with breast cancer was 50.4 months and observed 5 year survivalrate 69.7%.2. Breast cancer patient’s survival was correlated to age group and level of education.3. Breast cancer patient’s survival was correlated to stage of diagnosis and get involved cancertreatment.