ABSTRACT
Background : Stroke is a common, potentially devastating disease with potential high morbidity and mortality. EEG (Electro-encephalogram), functional representation of electrical activity of brain, changes are closely tied to CBF (Cerebral Blood Flow). Thus EEG is useful to establish the location of Ischaemic CVA (Cerebro-vascular accident). It can also prognosticate Ischaemic stroke. Aims & Objectives : (1) To assess the grade and severity of clinical manifestations in acute ischaemic stroke patients by clinical scoring following admission. (2) To obtain EEG findings of ischaemic stroke patients following admission and after 1 month. (3) To assess the morbidity of ischaemic stroke patients by Modified Rankin Scale after 1 month. (4) To correlate EEG changes according to the clinical outcome and according to the site of involvement of ischaemic stroke. Materials and Methods : 90 Patients were selected during the study period as per the inclusion and exclusion criteria. Clinical scoring was done by NIHSS (National Institute of Health Scoring System). CT (Computed Tomography) scan of brain and MRI (Magnetic Resonance Imaging) Brain with DWI (Diffusion Weighted Image) extension was done. EEG findings on admission of morbidity was done by Modified Rankin Score on follow up after 1 month was noted. EEG findings after 1 month was noted on follow up. Assessment Clinical correlation was compared with EEG changes. All the data were collected and analysed by statistical software SPSS version 20. Results : The mean MRS (Modified Rankin Score) after 1 month for abnormal EEG on admission was 4.50 in comparison to score of 3.36 in case of normal EEG. The p value of this association was 0.003 and was considered significant. Conclusions : Normal EEG and focal slowing of EEG was mostly noted in MCA (Middle Cerebral Artery) and PCA (Posterior Cerebral Artery) infarcts involving the cortical region. Those with normal EEG findings had good clinical outcome in comparison to those with abnormal findings in EEG
ABSTRACT
Introduction : Non-alcoholic Fatty Liver Disease (NAFLD), a hepatic manifestation of Metabolic Syndrome, has now become a Global Phenomenon and along with its increasing prevalence various morbidities and mortality are also increasing. Aims and Objectives : The objective of the present study was to establish whether patients with NAFLD, in the absence of other comorbid conditions suffer from cognitive impairment. Materials and Methods : This cross sectional study was conducted at the Department of General Medicine, Calcutta National Medical College and Hospital. 90 patients with NAFLD and 90 healthy controls were recruited after matching all the inclusion and exclusion criteria, from the out patient and in patient department over a period of 1 year starting March, 2019. NAFLD was diagnosed by noninvasive methods including Elastography (fibroscan). Cognition was assessed by MoCA (Montreal Cognitive Assessment test) score. Result : The mean age of cases and control were 49.2 and 48.5 years, respectively. Out of total cases and controls 48.9% was male and 51.1% was female. The mean BMI of the cases and control were 30.21�24 and 22.60�52 Kg/m2, respectively. The mean Elastography score among the cases was 4.91�23 kPa and that among the controls was 3.84�31 kPa. The mean Fibroscan Score among male cases and controls were 4.907�26 kPa and 3.83�35, respectively (p