ABSTRACT
Introduction: Eccrine spiradenoma is extremely rareadnexal tumor of the sweat gland, mainly affecting middleaged persons with equal incidence in males and females. Itis frequently a benign tumor characterized as solitary, painfuldeep - seated dermal nodule with most common sites being theupper thorax and face.Case report: A 35 year old male presented with multiple,painful swellings over scalp,face,anterior chest and backsince 6 months with loss of weight and appetite for 2 months.On examination, patient had a single cervical lymph node ofsize 1*1cm in the right posterior triangle of neck. Multipletender subcutaneous, hard, nonmobile swellings present overseveral areas with largest(2*1cm) over anterior chest wall.Histopathologically diagnosed as Eccrine spiradenoma whichrevealed clusters and sheets of cells having mild pleomorphicround to ovoid bland nuclei with indistinct cytoplasmicborders, occasional duct or follicular appearance and emptylooking lumina with no necrosis or mitotic activity.Conclusion: Eccrine spiradenoma, a rare benign adnexaltumor confirmed by histopathological examination.Differential diagnosis include, Neuroma, Dermatofibroma,Glomus tumor, Angiolipoma, Cylindromas and leiomyomas.Diagnosis confirmation by histopathological examination iscrucial because of its potential for malignant transformation.Its prognosis is poor as it has multiple recurrences.Histopathological examination is gold standard for thediagnosis.
ABSTRACT
Lymphoepithelioma like carcinoma is rare in locations other than nasopharynx. We report the second case of this tumour in trachea, in a young female patient, who was managed with concomitent surgery, radiotherapy and chemotherapy. The patient is disease free in the one-year follow up. The tumour presented difficulties during intubation for general anaesthesia and during surgery. Association with Epstein-Barr virus was not found in our case.
Subject(s)
Adult , Carcinoma, Squamous Cell/pathology , Combined Modality Therapy , Female , Humans , Tracheal Neoplasms/pathologyABSTRACT
Central retinal vein occlusion (CVO) is a common retinal vascular disorder with potentially blinding complications. However, a simultaneous bilateral affection is not a common entity. One such patient is described here.
Subject(s)
Adult , Diagnosis, Differential , Electroretinography , Female , Fluorescein Angiography , Fundus Oculi , Humans , Multiple Myeloma/complications , Retinal Vein/pathology , Retinal Vein Occlusion/diagnosisABSTRACT
Wilms' tumour, an embryonic neoplasm, the most common renal tumour in childhood, had occasionally been reported in adults. Authors report two such cases and have reviewed the relevant literature. While Wilm's tumour in children classically demonstrates the curative potential of combined modality treatment, no such clear guide lines are available for those occurring during adulthood. Pathologic diagnosis of adult Wilm's tumour is difficult because of the multiplicity of undifferentiated adult tumours that must be considered in the differential diagnosis. As no predictive parameters for optimal therapy exist, a combination of surgery, irradiation and chemotherapy probably is indicated for all stages of disease.