ABSTRACT
Purpose: To assess the association between radial peripapillary capillary (RPC) plexus using optical coherence tomography angiography (OCTA) and retinal nerve fibre layer (RNFL) thickness using spectral domain OCT (SD?OCT) in primary open?angle glaucoma (POAG) patients, glaucoma suspects, and healthy subjects. Methods: In this single?centre cross?sectional observational study, POAG, glaucoma suspects, and healthy patients underwent OCT?RNFL and optic nerve head angiography scans. The RNFL thickness and the vascular parameters obtained from RPC plexus, including perfusion density (PD), flux index (FI), and vessel density (VD), were analysed. Results: In all, 120 eyes of 120 patients, including 40 POAG patients, 40 glaucoma suspects, and 40 healthy subjects, were included. The pairwise comparison of mean RNFL thickness, FI, and VD showed significant difference (P < 0.001) in all sectors between POAG, glaucoma suspects, and healthy eyes. However, PD showed no significant difference between glaucoma suspects and healthy eyes. The average RNFL thickness was found to have a better diagnostic ability than VD to distinguish POAG eyes from healthy eyes and glaucoma suspects based on receiver operating characteristics curve and area under the curve. VD had better diagnostic accuracy than RNFL when glaucoma suspects and healthy were compared. Conclusion: OCT?RNFL has better diagnostic capability in differentiating glaucoma from healthy eyes compared to OCTA. However, OCTA was found to be better in screening out glaucoma suspects from healthy eyes. The VD is a better OCTA parameter than FI and PD to differentiate POAG and glaucoma suspects from healthy eyes
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Purpose: To compare the postoperative uncorrected distance visual acuity (UDVA) and refractive outcomes of cataract patients with astigmatism following implantation of Eyecryl™ and Tecnis® toric intraocular lenses (IOLs). Methods: We conducted a single?center, retrospective study including patients who had undergone phacoemulsification and implantation with either Eyecryl™ toric (Group 1) or Tecnis® toric (Group 2) IOL. The primary outcome measures included postoperative UDVA and residual astigmatism at 3 months. The secondary outcome measure was IOL misalignment >10° throughout the follow?up period. Results: One hundred and eight eyes of 76 patients (44 males and 32 females) were analyzed. Twenty?nine patients (38 eyes) received Eyecryl™ toric IOL (Group 1), and 47 patients (70 eyes) received Tecnis® toric IOL (Group 2). Groups 1 and 2 showed a mean postoperative logMAR UDVA of 0.09 ± 0.11 and 0.06 ± 0.09, respectively, at 3 months (P = 0.114). In both groups, all the eyes achieved a postoperative UDVA of ?0.3 logMAR. The postoperative residual astigmatism of group 1 and group 2 was ?0.29 ± 0.34 D and ?0.16 ± 0.27 D, respectively (P = 0.038). Postoperative astigmatism was within ± 1.00 D in all the eyes. No eyes had an IOL misalignment >10° throughout the follow?up period. Conclusion: Both Eyecryl™ and Tecnis® toric IOLs provided significant improvement in uncorrected visual acuity and astigmatism correction postoperatively. The Tecnis® toric IOL provided statistically significant lower residual astigmatism than Eyecryl™toric IOL. However, the difference in postoperative astigmatism between the two IOLs was clinically insignificant
ABSTRACT
AIM:To compare the corneal curvature and to investigate the agreement between three different keratometers.METHODS:In this prospective study,keratometry was performed using an IOL Master (IM),a Bausch &Lomb manual keratometer (Man) and TOPCON KR-8800autokeratometer (Top) on 252 eyes of patients recruited from camps for cataract surgery.The average keratometry values were recorded and compared.The agreements between the instruments were analyzed using the Bland-Altman statistical method.The main outcome measure was average keratometry values.RESULTS:1) IOL Master and Manual keratometer:the mean corneal power was 44.62± 1.52 D with the IOL Master and 44.60 ± 1.52 D with the Manual keratometer.The paired t-test demonstrated a statistically significant difference in the mean corneal power between the IOL Master and Manual keratometer (P=0.001).The 95％ LOAs of the two devices were-0.22 to 0.22 as shown in the Bland-Altman plot;2) IOL Master and autokeratometer:the mean corneal power was 44.62±1.52 D with the IOL Master and 44.46± 1.53 D with the autokeratometer.The paired t-test demonstrated a statistically significant difference in the mean corneal power between the IOL Master and autokeratometer (P＜ 0.0001).The 95％ LOAs of the two devices were-0.24 to 0.55 as shown in the Bland-Altman plot;3) Autokeratometer and Manual keratometer:the mean corneal power was 44.60±1.52 D with Manual keratometer and 44.46±1.53 D with the autokeratometer.The paired ttest demonstrated a statistically significant difference in the mean corneal power between the autokeratometer and Manual keratometer (P＜ 0.0001).The 95％ LOAs of the two devices were-0.30 to 0.57 as shown in the Bland-Altman plot.CONCLUSION:Keratometry data obtained with different instruments may not be interchangeable,a fact that has important implications for cataract surgeons with respect to both surgical planning and outcomes auditing.
ABSTRACT
To evaluate the safety and efficacy of iris claw intraocular lens (IOL) implantation for correction of monocular surgical aphakia in eyes with no capsular support. This is a prospective interventional case series of 30 eyes of monocular surgical aphakia. Patients underwent posterior iris claw implantation 4 weeks after the primary surgery. Aphakia which resulted due to posterior capsular rupture, large zonulo-dialysis (>180°) and cases of intracapsular cataract extraction in subluxated cataractous lens (>180°) where a posterior chamber IOL could not be placed were included in this study. Postoperatively, best-corrected visual acuity (BCVA) improved significantly (P < 0.02), 80% of patients had good vision of (20/20 to 20/40) and endothelial cell loss was 8.96% at 6 months. Secondary iris claw intraocular lens implantation is a viable option to correct monocular aphakia in eyes without capsular support.