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A 63-year-old male patient, who had a severely resorbed edentulous maxillary arch and partially edentulous mandibular arch decided on the implant-supported fixed treatment option to replace the edentulous maxillary arch. The fully guided implant placement that utilizes the computer-generated guide is more accurate than traditional surgical guides and free-hand placements. The researchers have correlated possible implant failure risk factors with age, sex, smoking, type of edentulism, bone quality and volume, implant location, angulation, diameter, length, and various systemic factors. This case report demonstrated the failure cause of virtually planned anterior implants in All-on-4 and how to manage it by free-hand surgery without surgical guides.
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Bones and joint disorders are common in the working age population and are conditions that affect passive (bones, joints) and/or active structures of the body (muscles, tendons, ligaments, peripheral nerves) . A 35 year old moderately built young gentle man working as an IT professional, complains of pain on nape of neck and back of the chest since one year. But however pain started radiating to left upper arm since past 4 months, night starts which apparently effecting sleep. Pain gets aggravated by physical activities like continuous sitting posture and gets relieved by analgesics and sleep at Chondroitin Sulphate. Cervical IVDP, can be considered as Apabahuka or Asthi majjagata vata . He was managed with external and internal medications like cervical traction, Lepanam, physio, Gandharvahasthadi kashayam, Sneha panam done with Gugguluthikthakam ghee, purgation done with Gandharvahasthadi erandam and Nasya done with Anutailam and Ksheerabala tailam
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In a completely randomized design, the experimental material should be homogeneous. Usually, the experimental materials are not so homogeneous in nature, particularly in agricultural ?eld experiments. In such a situation, the principle of local control is adopted and the experimental material is grouped into homogeneous subgroups. In this paper, cow milk data are used and applied four different types of treatments. The yield of a cow is analyzed and interpreted using Randomized Complete Block Design (RCBD). Results are explored, tabulated and interpreted
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To the editor, Sinus arrest and cardiac arrest are two different terms which are often confused by many. This confusion often leads to inappropriate cardiopulmonary resuscitation (CPR) when patient is connected to defibrillator. Sinus arrest is defined as transient pause in Sino-atrial firing for more than 3 s1. When sinus arrest occurs, other latent pacemakers (atrial myocardium, cells nearby atrioventricular node, and His purkinje system) usually starts firing until Sino-atrial node recover. Sinus arrest can be prolonged till other pacemakers starts firing2. Cardiac arrest occurs when these latent pacemakers does not take up the job of alternate firing. Prolonged sinus arrest in a defibrillator may look like a cardiac arrest which might lead to unnecessary CPR. Here, we would like the put forward a new term mechano - defibrillator dissociation which occurs because of prolonged sinus arrest. We should be aware this, so that inappropriate CPR could be avoided. We, emergency physician also faced similar situation while resuscitating a patient because of mechano - defibrillator dissociation caused by prolonged sinus arrest/pseudo cardiac arrest. A 52-year-old male diabetic, hypertensive, and chronic alcoholic came to our emergency department (ED) with history of giddiness, syncope, and palpitation. On arrival to ED, patient was drowsy, diaphoretic, and hypotensive. Patient was connected to defibrillator which showed a heart rate of 35/min and saturation was 90% in room air. ECG showed complete heat block (CHB) and point of care echocardiography showed reduced ejection fraction.
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Humans , Male , Middle Aged , Sinus Arrest, Cardiac , Letter , Cardiopulmonary Resuscitation , DefibrillatorsABSTRACT
Flemingia tuberosa Dalzell is an endemic species of the Western Ghats. It is an ethnomedicinal plant used to curedysentery and vaginal discharge. However, in this study, the hepatoprotective potency of the plant has been evaluatedas it contains flavonoids like kaempferol. The present study was conducted to investigate the hepatoprotective activityof the ethanolic extract of aerial parts of F. tuberosa against Carbon tetrachloride (CCl4)-induced toxicity in rats.The extract was standardized using a validated HPTLC method for kaempferol content. The antioxidant activityof the ethanolic extract of aerial parts of F. tuberosa was assessed by 1,1-diphenyl-2-picrylhydrazyl method. Thehepatoprotective activity was assessed against CCl4-induced liver intoxication, wherein the CCl4-induced albino Wistarrats were treated with three different doses of the standardized extract for 3 days. The results were compared with theestablished positive control, Silymarin. The protective effect on the liver was also monitored histopathologically usinglight and electron microscope and biochemically through observing the levels of biochemical enzymes. The extractshowed potent hepatoprotective activity. This study confirms the protective effect of the ethanolic extract of aerialparts of F. tuberosa against CCl4-induced hepatotoxicity
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Introduction: The association between diabetes and hearing loss has been a topic of discussion since many years. Type 2diabetes mellitus (DM) which is the most predominant form of diabetes worldwide, accounts for 90% of cases globally. DMis a chronic metabolic disorder characterized by high blood glucose level, associated with insulin resistance and relativeinsulin deficiency. DM is associated with a lot of complications; a lesser known complication is auditory organ dysfunction.The International Diabetes Federation estimated in 2014 that 387 million people have diabetes worldwide and that by 2035this number will rise to 592 million. Among these, 179 million are undiagnosed. In the United States, the Centers for DiseaseControl and Prevention estimated in 2014 that 29.1 million people had diabetes and that 8.1 million of them (27.8%) wereundiagnosed. These data reflect the late detection of hearing loss due to undiagnosed diabetes. Studies have indicated thatvascular changes which include thickening of capillary walls in the stria vascularis, neural changes in the cochlea, and loss ofouter hair cells are the causes of hearing changes in DM.Objective: The objectives are as follows: (1) Primary objective: To assess the prevalence of hearing loss in patients with Type 2DM when compared to non-diabetic patients and (2) secondary objective: To analyze the effect of age, glycemic control (HbA1c),and duration of diabetes on auditory acuity and to assess whether otoacoustic emission (OAE) can be used as a screeningtest for hearing assessment in diabetics.Materials and Methods of Study: The design of this study was hospital based observational prospective study carried outfrom February 2017 to July 2018. A total of 100 patients who presented to the ENT OP Department Sree Gokulam MedicalCollege and Research Foundation were studied by dividing into two groups; Group A consisted of 50 type 2 diabetic patientsand Group B consisted of 50 age- and gender-matched non-diabetic patients. The age group of the patients was between 30and 50 years. All the patients were subjected to Pure Tone Audiometry for the quantitative and qualitative assessment of hearingloss. Transient OAE (transient evoked OAEs [TEOAE]) was also done to know whether it can be used as a screening test forthe early detection of hearing loss. HbA1c was done in diabetic patients to detect any association with the hearing loss. Ageand duration of diabetes and its correlation with hearing loss were also assessed.Results: Our study confirmed the existence of sensorineural hearing loss (SNHL) in type II diabetic patients, mostly bilateralmoderate SNHL. Age and duration of diabetics had an association with SNHL. As the age increases, there is increase in theauditory thresholds and amount of hearing loss (AHL). Type 2 diabetic patients with long duration of diabetes also had higherauditory thresholds at all frequencies from 250 to 8000 Hertz (Hz), when compared to non-diabetic patients and the AHL wasalso higher as the duration of diabetes increased. HbA1clevel had no significant correlation with hearing loss. Theresult of TEOAE was refer, i.e. abnormal in all the patientswith hearing loss.Conclusion: The present study reports SNHL in 68% of type IIdiabetic subjects and 2% of healthy non-diabetic subjects.The majority of the patients had bilateral moderate SNHL.The diabetic patients had increased hearing threshold at all frequencies with gradual increase in hearing loss from 250 Hz to 8000 Hz. Age and duration of diabetes had a positive correlationwith hearing loss. As the age increased AHL also increased. Similarly, as duration of diabetes increased, AHL also increased.HbA1c had no relation with auditory threshold and AHL. TEOAE can be used as a screening test for the early detection ofhearing loss in Type 2 diabetic patients, as the result was abnormal in all the patients with hearing loss. Since hearing loss canbe considered to be a consequence of diabetes, a metabolic assessment may be useful for patients presenting with hearingloss so as to reduce the high rate of undiagnosed diabetes mellitus in the community. The use of audio logical tests to monitorhearing in diabetic patients should be considered as a routine procedure so that quality of life can be improved for long standingdiabetics with needed therapeutic interventions for hearing improvement.
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Background: Perforation peritonitis is one of the most commonly encountered surgical emergencies in our country. The prognosis of secondary peritonitis remains poor despite development in diagnosis and management. Early identification of patients with severe peritonitis may help in selecting patients for aggressive surgical approach.Methods: The study was conducted in 128 cases of perforation peritonitis admitted and treated in the department of surgery in a tertiary care centre. Initial diagnosis was made on the basis of detailed history, clinical examination and presence of pneumoperitoneum on erect abdominal X-ray. Patients were first assessed using a predesigned Performa, then MPI score was calculated for each patient and the patients were followed-up till death or discharge from the hospital.Results: The ROC curve analysis shows area under the curve was 0.986 with a standard error of 0.008, 95% CI (0.971 to 1.001), p<0.0001. In our study authors found that for the MPI score of 26, sensitivity was 91.3% and specificity was 92.4%, with a positive likelihood ratio of 12.01 and a negative likelihood ratio of 0.09. Age of the patient, presence of organ failure, associated malignancy, generalised type of peritonitis and the original MPI Score has got a significant association with the final outcome (i.e. p value <0.05).Conclusions: MPI is an excellent prognostic index for peritonitis with high accuracy in individual prognosis that is cheap, cost effective, easily measurable and reproducible. The study accentuates that early diagnosis, appropriate resuscitation and prompt surgical intervention still remain the keystones in the management of perforation peritonitis.
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Sugar acids are organic acids formed by the oxidation of carbonyl or hydroxyl group of monosaccharides to carboxylic acid group. D-xylonic acid derived via bioconversion of D-xylose is a promising platform chemical with various applications in food, chemical, agriculture, and pharmaceutical industries. The efficacy of a newly isolated culture identified as Pseudoduganella danionis to produce D-xylonic acid from D-xylose was investigated. The culture appeared to be potent for a feasible bioprocess development for xylonic acid production. Production medium containing 10 g/L D-xylose resulted in 6.5 g/L D-xylonic acid production after 120 h of incubation with 1% (v/v) inoculum of P. Danionis.
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Background : Supraglottic airway devices are quicker airway control devices even in inexperienced personel. It has better hemodynamic control, less complications and better avoids the disadvantages of the ET insertion. In our study, We compare the performance of CLASSIC LMA and AMBU LMA in minor gynecological procedures. Materials & Methods : In a Prospective randomised case control study, 30 patients in each group were enrolled. size 3 or 4 LMA was used in all adult patients under General anaesthesia without muscle relaxant. Results : AMBU LMA has 90% ease of insertion, 93.3% in first attempt, less time taken for insertion (15 seconds), better hemodynamic control in 5 minutes compared to CLASSIC LMA ( 63%,83.3%,24seconds respectively). Complications like sore throat, blood stain in throat is comparable in both LMA. Conclusion : AMBU LMA has superior performance compared to CLASSIC LMA, and has no significance in view of complications like sore throat.
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Introduction: Life style of humans, with changes in diet, exercise and life style practices which play an important role in enhancing the progression of age related degenerative problems like dementia. The most common cause of dementia in the world is Alzheimer’s disease which ultimately decrease the cognitive function mainly learning and memory. The objective of the study was to find the multi target potential efficacy of the ligands, Glabridin and Diosmetin in altering the two main molecular targets of Alzheimer’s disease (AD). The target enzymes were amyloid binding alcohol dehydrogenase (ABAD) and β-site amyloid precursor protein cleaving enzyme 1(BACE1). Material and methods: In this study, we analyzed that multitarget potential of the two natural compounds on the two prior target enzymes of Alzheimer’s disease which are mainly involved in producing neurodegeneration. Drug likeness properties, absorption, digestion metabolic and toxicity profile and molecular docking were analyzed to determine therapeutic aspect by virtual methods. Results: Binding energy and Vander Waals force of Diosmetin were higher than Glabridin with the target ABAD and less than with BACE1 which showed that both drugs can be used in modulating the enzyme phosphorylation in Alzheimer’s disease. Conclusion: Glabridin and Diosmetin could be used as promising drug candidates as ABAD inhibitor and BACE1 inhibitor in Alzheimer’s disease
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Background and Objective: Background and objective of the study were to determine how well the pre-operative multidetectorrow computed tomography (MDCT) findings and intraoperative endoscopic sinus surgery findings correlate in patients withchronic rhinosinusitis (CRS) and to assess the various anatomical variations of the osteomeatal complex in these patients.Materials and Methods: A total of 100 patients falling within the inclusion criteria with diagnosed CRS who had given consentfor participating in this study were analyzed. The study period was from January 2016 to December 2016. In these patients, adetailed history and examination were done, counseled regarding the necessity of MDCT scan imaging of the nose and sinusesand further about the need for endoscopic evaluation and functional endoscopic sinus surgery (FESS). Scans were evaluatedpreoperatively as per Lund–Mackay CT scan score and anatomic variants regarding OMC were noted. Later, intraoperativefindings were noted, and kappa statistics was used to analyze the agreement between MDCT and intraoperative endoscopicfindings.Results: Agger nasi, concha bullosa, medial and lateral deviation of the uncinate process and paradoxical middle turbinateshowed a very good correlation of agreement between pre-operative CT scan and operative findings. Excellent correlationwas found in case OMC obstruction, and there was a very good correlation of agreement between pre-operative CT scan andoperative findings.Conclusion: MDCT shows an increased sensitivity compared to routine CT in detecting OMC obstruction, and it had a verygood correlation with intraoperative findings. There was an excellent correlation between MDCT and intraoperative findingsin cases of all anatomic variants studied except concha bullosa. In conclusion, MDCT can help clinicians to better predict theOMC status pre-operatively and thereby guide FESS
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The Banking industry is the backbone of every economy and has a major role to play in the wellbeing of a nation. The competition in the banking sector is so severe that the banks are finding it very difficult to increase their market share. Acquiring customers as well as retaining them is a big challenge faced by them. Banks have to capitalize on service delivery so as to ensure customer satisfaction and customer loyalty. Therefore, the banks have to formulate clear strategies in meeting the dynamic customer demands and ensuring customer satisfaction. The objective of this research is to ascertain factors influencing customer loyalty amongst the banking customers in Trichy District. Descriptive research was carried out in identifying the problems as well as developing the concepts of this research. A total of the sample size of this research is 420 customers. Various research tools like Cronbach’s alpha test, ANOVA, correlation, and a weighted arithmetic mean were employed in this study. The research found that Brand awareness and Perceived Quality are the strongest factors in generating brand loyal customers. These factors have a greater role in modern day banking to ensure customer satisfaction and provide the edge over the competitors.
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This study was carried out on 80 dry human sacra in meenakshi medical college Anatomical variations inmorphology and morphometry of sacral hiatus. Various shapes of sacral hiatus were observed which includedinverted U (66.3%), inverted V (11.3%), irregular (11.3%), dumbbell (3.8%) Agenesis Of the dorsal (6.3%) and bifid(1.3%). The apex of sacral hiatus was commonly found at the level of 4th sacral vertebra in 76.0%. the meanlength of sacral hiatus was 22.9 mm. The mean anteroposterior diameter of sacral canal at the apex of sacralhiatus was 4.97 mm. Narrowing of sacral canal at the apex of sacral hiatus, diameter less than 4mm, wasobserved to be significantly high, (36%). The knowledge of anatomical variations of sacral hiatus is significantwhile administration of caudal epidural anaesthesia and it may help to improve its success rate
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Background: Foot complications are found to be a significant frequent, complication of Diabetes mellitus. Carbapenem-resistant Acinetobacter baumannii is gradually becoming dominant among Diabetes patients in urban population. The purpose of this study was to evaluate the clinical relationship of these gram negative bacteria and their resistance mechanisms in patients with diabetic foot and infected ulcer in India. Methods: An observational study of 532 patients with infected ulcers in diabetic feet was conducted in Hycare for Wounds a tertiary care centre exclusively dedicated for Wound care and Management between May, 2017 and April, 2018. Processing and identification was done as per standard guidelines. The bacteriological assessment was performed in deep tissue cultures and amputation was considered major when performed above the foot’s middle tarsus. Results: Out of 532 patients studied 350 were positive for bacterial growth. Commonest isolate was Pseudomonas aeruginosa followed by Staphylococcus aureus (MSSA) species, Klebsiella and E. coli. We observed that 14 patients were infected with Acinetobacter baumannii and 50 % were carbapenamase producers. Clinical Outcomes: Out of 14 patients 6 were major amputees and 5 were minor amputees and the rest 3 patients are under medical management. Conclusion: Carbapenem-resistant Acinetobacter baumannii is a serious threat to Diabetic patients and can be considered as a risk factor for major amputation.
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A 36-year-old female presented with the complaints of pain, photophobia, redness, and sudden diminution of vision in both the eyes following topiramate for migraine treatment. On examination, there was panuveitis with angle-closure glaucoma in both the eyes with fibrinous exudate with pigments in the anterior chamber of the left eye. B scan revealed increased choroidal thickness in both the eyes. Serial anterior segment optical coherence tomography scans were done in the left eye to demonstrate the gradual resolution of the fibrin material from the anterior chamber. There was complete resolution of inflammation in both eyes following discontinuation of topiramate and treatment with systemic and topical steroids. There was an improvement in visual acuity in the left eye following complicated cataract surgery.
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Multiple Sclerosis (MS) is a chronic progressive disease with a variety of cognitive, motor and sensory deficits. It is characterised by demyelination of axons of the brain and spinal cord where the patient presents with the complaints of blurred or double vision, lack of coordination, loss of balance, numbness and tremors throughout the body or extremities with weakness, muscle spasms etc. In Ayurveda, Multiple Sclerosis can be correlated to Snayusada or the aggravation of Vata in Snayu. Modern treatments like immunosuppressant, corticosteroids, stem cell therapy are highly expensive when compared to Ayurvedic management. The scope of Ayurvedic Management and preventive aspects mainly concentrates on improving the quality of life and decrease dependency of patients. The objective of this review is to evaluate the clinical utility of the Ayurvedic medicines for Multiple Sclerosis. Clinical trials by Ayurvedic experts suggest that Ayurvedic treatment processes and preventive measures (Life style management and recommended diet) may reduce the risk of Multiple Sclerosis. Here I briefly explain the current literature of Multiple Sclerosis, modern and Ayurvedic views, Ayurvedic medicines usually given in Multiple Sclerosis cases with a focus on designing prevention and treatment protocol.
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Background: Cucurmin is the main component of curcuminoids in turmeric (Curcuma longa). Turmeric, popularly used as food colourant, is traditionally used as a medicinal herb owing to its antioxidant, anti-inflammatory, antimicrobial and anticancer properties. The gastric absorption of curcumin is poor and therefore various forms like encapsulation in liposomes, polymeric nanoparticles, cyclodextrin encapsulation, lipid complexes, polymer-curcumin complex etc. have been evaluated.Methods: In the current study, a novel lozenge of 100mg turmeric extract in mouth dissolving formulation is evaluated for bioavailability of curcumin as compared with the conventional hard gelatin capsule containing 475mg curcumin. Fourteen healthy male subjects of Indian origin are dosed in a two way, two treatments, two sequence cross-over balanced, randomized design. Blood samples are collected sequentially to cover the plasma concentration-time curve to obtain a reliable estimate of the extent of absorption. Blood plasma is processed and analyzed using a validated isocratic HPLC-MS/MS method to estimate the concentration of curcumin.Results: Curcumin is detected at m/z 369à177, while the internal standard diazepam is detected as m/z 285à193 to quantify curcumin. Results indicate a significant increase in bioavailability of curcumin from the lozenge (Cmax188.863±22.9620ng/ml; AUC0-t 897.026±65.4844ng/mL*hr) as compared to the hard gelatin capsule (Cmax 96.458±15.8272ng/ml; AUC0-t 440.744±77.3470ng/ml*hr).Conclusions: Mouth dissolving lozenge could be a pragmatic approach to circumvent the low bioavailability of curcumin from therapeutic formulations.
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Introduction: Cardiac disease is a major risk factor for stroke, ranking third after age and hypertension. Congestive Cardiac failure ranks second in cardiogenic stroke risk. The prevalence of cardiac failure increases substantially in prevalence as the population ages. Cardiac failure is also associated with high mortality, with a 15 year total mortality rate estimated at 39% for women and 72% for men. LVSD is common and treatable, accounting for 8%of people aged 25-75 years and 12% of 45-75 years. Of the 8%, 4% are asymptomatic6. The patients who appear to be at high risk of LVSD are those with ischaemic heart disease, hypertension or diabetes, and smokers. Aim of the study: Assessment of Left Ventricular Function in Ischaemic Stroke Patients. Materials and methods: LV function was assessed by Trans thoracic 2 - dimensional echo cardiography in patients admitted with ischaemic stroke under various medical units of our government hospital. Results: 142 Patients of the study group were divided into various sub groups. Ischaemic stroke was most commonly observed between 51-60 years of age followed by patients aged 61-70 years .The mean age of the patients was 58 years. All of these patients were men. Out of 94 men, 73 patients were chronic smokers (51%). The mean age of the smokers was 54 years. Associated history of chronic alcohol intake was seen in 33 male patients. Associated hypertension was seen in 11 patients who had statistical significance (P- value .00). Coexisting diabetes mellitus was observed in 8 patients. This correlation had a statistical significance (P- value .01) Prior history of coronary artery disease was obtained in 6 patients. This was not statistically significant. Hypercholesterolemia was noticed in 42 patients. Past history of stroke was present in 25 patients. History of shortness of breath of varying degree suggestive of left heart failure was observed in 20 patients. Conclusion: LVSD was observed in 30 patients of the present study (21.13%).Diastolic dysfunction was observed among 12 patients (3.4%).Association of LVSD with clinical severity and extent of the P. Sasikumar, P. S. Rani. Assessment of left ventricular function in ischemic stroke in GDMCH Dharmapuri. IAIM, 2017; 4(6): 64-70. Page 65 stroke had of positive correlation statistically .Association of LVSD with in hospital stay mortality was not significant. Hypercholesterolemia was observed as the most common risk factor among the ischaemic stroke patients. Coexisting coronary artery disease and diabetes mellitus had positive correlation with left ventricular systolic dysfunction.
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Introduction: The incidence of diabetes in India is 3.8%34. It is well known that diabetes is a systemic disease; it affects almost all organ systems. Non-alcoholic fatty liver disease (NAFLD) is being increasingly recognized today as a potentially serious complication of diabetes, especially type 2. The spectrum of NAFLD extends from simple steatosis or steatosis with mild inflammation to severe non-alcoholic steatohepatitis (NASH). Aim of the study: The Aim was to analyse the prevalence of Fatty Liver (Non Alcoholic Fatty Liver Disease) in Patients with Diabetes. Materials and methods: The study was to be conducted in Government Dharmapuri Medical College Hospital, Dharmapuri, and Tamil Nadu. It was an observational type of study. Interview technique was used to collect information on a predesigned proforma. All diabetes patients both type 1 and type 2. Both male and female patients were included in the study. Results: Among the 75 diabetics who were studied, fatty liver was found in 31patients (41.33%). No. of patients with fatty liver was 31. No. of patients without fatty liver was 44. The number of males with fatty liver were 2 (2.6%) and females 29 (38.6%). The number of patients with fatty liver who had central obesity (waist hip ratio >1) was 23 (74.19%). All the patients with fatty liver had central obesity (waist hip ratio >1 in males and >0.85 in females). Conclusion: The prevalence of non-alcoholic fatty liver disease was 41.3% and it was present mainly in patients with type 2 diabetes mellitus. It occurred more commonly in women (38.66%) than men.
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Background: Despite impressive strides in diagnosis and management of acute myocardial infarction in the past three decades, acute myocardial infarction continues to be a major health problem. About 50% of death from acute myocardial infarction occur within 1 hour of the event and are attributable to arrhythmias most often ventricular fibrillation. Ischemic injury can produce conduction blocks at any level of the atrioventricular or Intraventricular conduction systems. Such conduction block can occur in the atrioventricular node producing various grades of AV block. Conduction block can occur in either main bundle branch producing right or left bundle branch block or in the anterior and posterior fascicle of left bundle branch, producing left anterior &left posterior fascicular blocks respectively. Aim of The Study: To study the incidence of rhythm disturbances in acute myocardial infarction, to evaluate the age, sex distribution and various other risk factors in relation to rhythm disturbances occurring in acute myocardial infarction, to correlate between the different types of rhythm disturbances in relation to the location and type of acute myocardial infarction. Materials and methods: The study was conducted in Government Dharmapuri Medical College Hospital during the period from November 2016 to May 2017. The patients admitted to ICCU were taken up for study. A detailed history physical examination &laboratory work up was done in all patients. Results: 100 Patients of acute myocardial infarction were included in this study. They consisted of 77 male and 23 female patients. The youngest patient was a 23 year old male and the oldest patient was an 84 year old male. Out of 100 patients with myocardial infarction 80 were males and 20 were females. Out of 80 males 37 had rhythm disturbances with a percentage of 46.25 and out of 20 P. Sasikumar. Study of rhythm disturbances in acute myocardial infarction in Government Dharmapuri Medical College Hospital, Dharmapuri. IAIM, 2017; 4(7): 207-212. Page 208 females 9 had rhythm disturbance with a percentage of 45. 8 patients had previous ischemic heart disease prior to present episode. Of these 4 developed rhythm disturbances. All female patients were postmenopausal. 6 patients had COPD and 3 developed rhythm disturbances. Out of 100 patients 25 patients had Intraventricular block, of these right bundle branch block was common with an incidence of 10. Conclusion: The distribution of rhythm disturbances were almost equal in males and females ( p value 0.3365). Rhythm disturbances were more common in the age group 50-59. The incidence of rhythm disturbances in patients with Diabetes mellitus and hypertension was high.