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1.
Article in English | IMSEAR | ID: sea-43469

ABSTRACT

Fifty patients (26 males and 24 females) who underwent tonsillectomy were then treated with injection of the long acting steroid (Kenacort-A) into the right tonsillar fossa after the operation. The left side was used as the control. Post-operative pain was assesed by the patients and was graded and recorded daily as mild, moderate, and severe pain on both sides of the throat for 2 weeks. A significant reduction of pain in the tested side (right side) was noted in the majority of the patients. The duration of pain was shorter in the right side than the left side. It seemed to significantly reduce the post-tonsillectomy pain. Because of its simplicity, cost effectiveness, and no complications, the technique should be used for pain-free tonsillectomy in non-contraindicated cases.


Subject(s)
Adolescent , Adult , Anti-Inflammatory Agents/administration & dosage , Case-Control Studies , Child , Chronic Disease , Dose-Response Relationship, Drug , Female , Humans , Injections, Intralesional , Male , Pain Measurement , Pain, Postoperative/drug therapy , Probability , Prospective Studies , Reference Values , Severity of Illness Index , Tonsillectomy/methods , Tonsillitis/diagnosis , Treatment Outcome , Triamcinolone/administration & dosage
2.
Article in English | IMSEAR | ID: sea-44404

ABSTRACT

Osseous choristoma represents the dense, mature, bony tissue in an abnormal location. We reported three cases of lingual osseous choristoma, herein, a year after the report of eight cases in 1998. All three lesions were at or close to the foramen caecum. The lesions were smooth, round or lobulated and pedunculated in shape and stony hard in consistency. All of them were preoperatively diagnosed, based on the above unique clinical findings without any radiography. The lesions were simply excised without local recurrence.


Subject(s)
Adolescent , Adult , Bone and Bones , Choristoma/diagnosis , Female , Follow-Up Studies , Humans , Tongue Diseases/diagnosis , Treatment Outcome
3.
Article in English | IMSEAR | ID: sea-44571

ABSTRACT

The efficacy and safety of 0.3 per cent Ofloxacin otic solution (OFLX) 6 drops twice daily was compared with those of oral Amoxycillin 500 mg three times daily plus 1 per cent Chloramphenicol ear drop at 3 drops three times daily (AMOX + CRP) in a two-week treatment of chronic suppurative otitis media (CSOM) with acute exacerbation. 80 adult patients were enrolled in a prospective, randomized, investigator-blind study at the outpatient ENT service of Chulalongkorn University Hospital. The most common pathogens isolated at the pretreatment visit were Staphylococcus aureus (30.3%) and Pseudomonas aeruginosa (24.7%). The susceptibility of all the pathogenic isolates to ofloxacin, amoxycillin and chloramphenicol were 96.4, 57.1 and 51.8 per cent respectively. The overall response expressed as an improvement or cure of otalgia, otorrhea and middle ear mucosal inflammation was recorded. It revealed that the improvement rate of the OFLX-treated patients was better than that of AMOX + CRP-treated, but was not statistically significant. However, the cure rate was significantly better in OFLX-treated than in AMOX + CRP-treated groups in terms of painless (p = 0.05) and dry (p < 0.001) ears. Ototoxicity was assessed by an elevation in bone conduction threshold (BC) and/or speech reception threshold (SRT) of greater than 5 dB or a presence of high tone hearing loss resulting from treatments. A significant decrease in BC and SRT was revealed in OFLX-treated ears (p < 0.0001; p = 0.002 respectively) but a significant elevation of BC was found in AMOX + CRP-treated ears (p = 0.007). The ototoxic rate was significantly higher in AMOX + CRP-treated than in OFLX-treated ears whether assessed by BC (p < 0.001) or SRT (p = 0.03). In conclusion, OFLX was more effective and safer than AMOX + CRP in the treatment of CSOM with acute exacerbation.


Subject(s)
Administration, Oral , Administration, Topical , Adolescent , Adult , Aged , Amoxicillin/administration & dosage , Anti-Infective Agents/administration & dosage , Chi-Square Distribution , Chloramphenicol/administration & dosage , Chronic Disease , Double-Blind Method , Drug Therapy, Combination/administration & dosage , Female , Follow-Up Studies , Humans , Male , Middle Aged , Ofloxacin/administration & dosage , Otitis Media, Suppurative/diagnosis , Penicillins/administration & dosage , Prospective Studies , Recurrence , Treatment Outcome
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