Prediction of weight of Indian children aged upto two years based on foot-length: implications for emergency areas.

BACKGROUND: Children presenting in critical care department might receive improper drug doses, as their weight and length cannot be determined while they are being resuscitated. AIMS: To determine if there is a correlation between foot-length and weight, length and surface area and to compare the drug doses calculated as per predicted weight (determined on the basis of foot-length) with those calculated on the basis of actual weight. MATERIAL AND METHODS: Weight, length and foot-length of children aged up to 24 months were determined in the prospective study. Analysis was done using simple linear regression analysis and by determination of coefficient of determination. The dosages of emergency medications (epinephrine, atropine, Ringers lactate and diazepam) were calculated on the basis of actual weight and dosages given in standard text and were then compared with dosages likely to be administered on the basis of weight predicted by foot-length measurement. RESULTS: Five hundred subjects were enrolled in the study that demonstrated a significant linear relationship between foot-length and body weight (r2 = 0.88), total length (r2 = 0.88), and body surface area (r2 = 0.84). The weight could be predicted on the basis of the following formula Weight (kg)= [1.35 x foot-length (cm)] -5.15. The doses of drugs calculated on the basis of weight predicted from foot length were exceeded the standard dose by 2.35 to 2.40%. CONCLUSIONS: In children aged up to 2 years, foot-length can be used to predict weight and calculate doses of emergency drugs.

Kocher-Debre-Semelaigne syndrome: hypothyroidism with muscle pseudohypertrophy.

Kocher-Debre-Semelaigne syndrome is a rare association of muscular pseudohypertrophy and hypothyroidism in children. We report two cases of this syndrome in this communication. The first case was a seven-years-old female who presented with features of hypothyroidism and muscle pseudohypertrophy. The second child had similar manifestations but was only fifteen months of age at diagnosis. This is one of the youngest patients reported to have the Kocher-Debre-Semelaigne syndrome. A short review of the literature is also presented.