ABSTRACT
The aim of the study was to investigate the antimicrobial susceptibility pattern of Klebsiellaspecies from different clinical samples at Sree Balaji Medical College and Hospital, India. Overall 189 samples out of 980 non repetitive clinical samples obtained from wound/pus, urine, sputum swab and blood by disc diffusion method and identified as Klebsiellaand analysed. Out of total 189 Klebsiellaisolates, 76 out of 155 K. pneumoniae(49%)were resistant and none out of 34 Klebsiella oxytoca(0%) showed resistance to cefotaxime and ceftazidime by disc diffusion method. Antimicrobial susceptibility testing of Klebsiellaexhibited 100% resistance to Ampicillin. The present study highlights the need for the continued monitoring of antimicrobial susceptibility patterns of important bacterial pathogens, so that rational antibiotic policies can be formulated