ABSTRACT
Dibucaine Number (DN) was determined in 103 patients suffering from duodenal ulcer diagnosed radiologically and 214 normal subjects (control). Statistically significant (p less than 0.001) difference was observed in the distribution of DN in the two groups. Whereas 94% of the control subjects had normal DN (above 70), 6% had intermediate DN (between 40--70) and none had atypical DN, only 32% of patients suffering from duodenal ulcer had normal DN, 64% had intermediate DN and 4% had atypical DN. The results have been discussed.
Subject(s)
Adult , Cholinesterase Inhibitors/analysis , Cholinesterases/blood , Dibucaine/pharmacology , Duodenal Ulcer/enzymology , Female , Humans , Male , Middle Aged , SpectrophotometryABSTRACT
1. Spectrophotometric determination of ampicillin showed comparable results with microbiological assay. 2. A bioavailability study with five brands of ampicillin revealed variations in the serum concentration at 3 hr. but showed somewhat similar concentrations at 6 hr. The results have been discussed.