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1.
Lysosomal membrane stabilization by antiinflammatory drugs.
Rao, A B; Sisodia, P; Sattur, P B.
Indian J Exp Biol ; 1989 Dec; 27(12): 1097-8
Article in English | IMSEAR | ID: sea-57584

ABSTRACT

Lysosomal enzymes are important mediators of acute and chronic inflammatory diseases. The release of lysosomal enzymes into cytoplasm stimulate the inflammatory mediators like oxygen radicals, prostaglandins etc. Enfenamic acid, a fenamate, along with other antiinflammatory drugs, did not stabilize lysosomal membrane isolated from normal and activated phagocytic polymorphonuclear leucocytes of different species.


Subject(s)
Animals , Anti-Inflammatory Agents/pharmacology , Guinea Pigs , Lysosomes/drug effects , Neutrophils/drug effects
2.
Influence of non-steroidal antiinflammatory agents (NSAIA) on chlorpropamide induced hypoglycemia in rats.
Diwan, P V; Karwande, I; Sattur, P B.
Indian J Exp Biol ; 1988 May; 26(5): 363-4
Article in English | IMSEAR | ID: sea-57165

Subject(s)
Animals , Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Blood Glucose/metabolism , Chlorpropamide/antagonists & inhibitors , Female , Male , Rats , Rats, Inbred Strains
3.
Antiinflammatory drugs--lysosomal membrane stabilization in normal and activated phagocytic cells.
Rao, A B; Sisodia, P; Sattur, P B.
Indian J Exp Biol ; 1988 May; 26(5): 365-7
Article in English | IMSEAR | ID: sea-60247

Subject(s)
Animals , Anti-Inflammatory Agents/pharmacology , Granulocytes/drug effects , Guinea Pigs , Humans , Intracellular Membranes/drug effects , Lysosomes/drug effects , Macrophage Activation/drug effects , Macrophages/drug effects , Male , Rabbits , Rats
4.
Erythrocyte membrane stabilization by enfenamic acid.
Bhaskar Rao, A; Sisodia, P; Sattur, P B.
Indian J Exp Biol ; 1987 Jul; 25(7): 489-90
Article in English | IMSEAR | ID: sea-62732

Subject(s)
ortho-Aminobenzoates/pharmacology , Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Aspirin/pharmacology , Erythrocyte Membrane/drug effects , Hemolysis/drug effects , Humans , Phenylbutazone/pharmacology
5.
Lysosomal membrane stabilization by enfenamic acid.
Rao, A B; Sisodia, P; Janardhan, A; Sattur, P B.
Indian J Exp Biol ; 1986 Dec; 24(12): 771-2
Article in English | IMSEAR | ID: sea-62795

Subject(s)
Animals , ortho-Aminobenzoates/pharmacology , Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Intracellular Membranes/drug effects , Liver/ultrastructure , Lysosomes/drug effects , Male , Rats , Rats, Inbred Strains
6.
Bioavailability and pharmacokinetics of enfenamic acid.
Rao, A B; Sisodia, P; Krishna, D R; Sattur, P B.
Indian J Exp Biol ; 1986 Nov; 24(11): 714-6
Article in English | IMSEAR | ID: sea-63381

Subject(s)
ortho-Aminobenzoates/blood , Anti-Inflammatory Agents, Non-Steroidal/blood , Biological Availability , Dosage Forms , Humans , Kinetics
7.
Inhibition of superoxide anion production from activated phagocytes by antiinflammatory drugs.
Rao, A B; Sisodia, P; Janardhan, A; Sattur, P B.
Indian J Exp Biol ; 1986 Oct; 24(10): 644-6
Article in English | IMSEAR | ID: sea-57115

Subject(s)
Animals , Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Guinea Pigs , Macrophages/drug effects , Male , Neutrophils/drug effects , Superoxide Dismutase/metabolism , Superoxides/metabolism
8.
Protein binding studies of enfenamic acid.
Rao, A B; Sisodia, P; Janardhan, A; Sattur, P B.
Indian J Exp Biol ; 1986 Jun; 24(6): 395-6
Article in English | IMSEAR | ID: sea-62438

Subject(s)
ortho-Aminobenzoates/blood , Humans , Kinetics , Protein Binding , Serum Albumin/metabolism
9.
Effect of enfenamic acid on prostaglandin synthesis.
Rao, A B; Sisodia, P; Janardhan, A; Sattur, P B.
Indian J Exp Biol ; 1986 Apr; 24(4): 246-7
Article in English | IMSEAR | ID: sea-62819

Subject(s)
Animals , ortho-Aminobenzoates/pharmacology , Arachidonic Acid , Arachidonic Acids/metabolism , Female , Guinea Pigs , Lung/drug effects , Male , Prostaglandin-Endoperoxide Synthases/metabolism , Prostaglandins/biosynthesis
10.
Studies on two new derivatives of N-aralkyl-O-ethoxybenzamides: Part III-pharmacological & biochemical studies on their anti-arthritic activity in rat.
Naik, S R; Sattur, P B; Sheth, U K.
Indian J Exp Biol ; 1979 Dec; 17(12): 1353-6
Article in English | IMSEAR | ID: sea-58993

Subject(s)
Animals , Anti-Inflammatory Agents/pharmacology , Arthritis/drug therapy , Aspirin/pharmacology , Benzamides/pharmacology , Connective Tissue/drug effects , Indomethacin/pharmacology , Male , Phenylbutazone/pharmacology , Rats
11.
Effect of nonsteroidal anti-inflammatory agents and diuretics in nephrotic syndrome patients.
Kshirsagar, N A; Shah, B P; Paul, T; Acharya, V N; Sattur, P B; Sheth, U K.
Article in English | IMSEAR | ID: sea-20061

Subject(s)
ortho-Aminobenzoates/therapeutic use , Anti-Inflammatory Agents/therapeutic use , Diuretics/therapeutic use , Drug Interactions , Drug Therapy, Combination , Furosemide/therapeutic use , Glomerular Filtration Rate/drug effects , Indomethacin/therapeutic use , Metolazone/therapeutic use , Nephrotic Syndrome/drug therapy , Platelet Aggregation/drug effects
12.
Studies on two new derivatives of N-aralkyl-o-ethoxybenzamides: Part I--pharmacological studies on anti-inflammatory activities.
Naik, S R; Sheth, U K; Bhanumati, S; Sattur, P B.
Indian J Exp Biol ; 1978 Nov; 16(11): 1169-74
Article in English | IMSEAR | ID: sea-59621

Subject(s)
Animals , Anti-Inflammatory Agents/therapeutic use , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Arthritis, Experimental/drug therapy , Benzamides/therapeutic use , Edema/drug therapy , Ethyl Ethers , Granuloma/drug therapy , Male , Mice
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